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ABCB6 Antikörper (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6) AA 440-455 Primary Antibody

ABCB6 Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (2 references)
Produktnummer ABIN129698
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle ABCB6 Antikörper anzeigen
    ABCB6
    Bindungsspezifität
    • 15
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 440-455
    Reaktivität
    • 34
    • 21
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 32
    • 3
    Kaninchen
    Klonalität
    • 33
    • 2
    Polyklonal
    Konjugat
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ABCB6 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 13
    • 13
    • 9
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Hund
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 440-455 of human ABCB6 protein.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity-purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 94 kDa in size corresponding to ABCB6 protein by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/ml
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Nakayama, Otsuka, Kobayashi, Okajima, Matsumoto, Hagiya, Inoue, Shuin, Nakajima, Tanaka, Ogura: "Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy." in: Scientific reports, Vol. 6, pp. 36478, (2016) (PubMed).

    Fukuda, Aguilar-Bryan, Vaxillaire, Dechaume, Wang, Dean, Moitra, Bryan, Schuetz: "Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8481-92, (2011) (PubMed).

  • Target
    ABCB6
    Andere Bezeichnung
    ABCB6 (ABCB6 Produkte)
    Synonyme
    ABCB6, abcb6, ABC, ABC14, LAN, MCOPCB7, MTABC3, PRP, umat, 1200005B17Rik, ATP binding cassette subfamily B member 6 (Langereis blood group), ATP binding cassette subfamily B member 6, ATP-binding cassette, sub-family B (MDR/TAP), member 6a, ATP-binding cassette, sub-family B (MDR/TAP), member 6, ABCB6, abcb6a, abcb6, Abcb6
    Hintergrund
    This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. ABCB6 (ATP-binding cassette sub-family B member 6, also known as mitochondrial precursor ABC transporter 3, Mt-ABC transporter 3, and ABC transporter umat) is a member of the superfamily of ATP-binding cassette (ABC) transporters.  ABCB6 is a membrane-associated protein that transports various molecules across the extra- and intra-cellular membranes.  ABC genes are divided into seven distinct subfamilies (ABC1, DR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily confer multi-drug resistance (MDR) to cancer cells and are also involved in antigen presentation. ABCB6 also likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
    Synonyms: ABC antibody, ABC transporter umat antibody, ABC14 antibody, ATP binding cassette sub family B member 6, mitochondrial precursor antibody
    Gen-ID
    10058, 13123949
    UniProt
    Q9NP58
    Pathways
    Transition Metal Ion Homeostasis
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