CD42b Antikörper (AA 19-129)

Produktnummer ABIN394943

Produktdetails anti-CD42b Antikörper

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Bindungsspezifität: AA 19-129

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD42b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Kreuzreaktivität (Details): Human: ~~ Positive

Aufreinigung: This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen:

Antigen Type: Recombinant Protein

Target/Specificity: GP1BA (AAH27955, 19 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 1C6

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Clear, colorless solution in phosphate buffered saline,  pH 7.2 .

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles

Haltbarkeit: 6 months

Details zu CD42b

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Andere Bezeichnung: GP1BA (GP1BA Produkte)

Synonyme: BDPLT1 antikoerper, BDPLT3 antikoerper, BSS antikoerper, CD42B antikoerper, CD42b-alpha antikoerper, DBPLT3 antikoerper, GP1B antikoerper, GPIbA antikoerper, VWDP antikoerper, GP1BA antikoerper, GPIba antikoerper, GPIbalpha antikoerper, glycoprotein Ib platelet alpha subunit antikoerper, glycoprotein Ib (platelet), alpha polypeptide antikoerper, glycoprotein 1b, alpha polypeptide antikoerper, GP1BA antikoerper, Gp1ba antikoerper

Hintergrund:

Other Names: Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, CD42b, Glycocalicin, GP1BA

Gene Description: glycoprotein Ib (platelet), alpha polypeptide

Gene Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq

Molekulargewicht: 68955 DA

Gen-ID: 2811

UniProt: P07359