CD42b Produkte
(Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))
Kategorien
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010].
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Ausgewählte CD42b Kategorien
CD42b Antikörper
High quality antibodies with extensive validation data.
CD42b ELISA Kits
Reliable ELISA kits for a wide range of species.
CD42b Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CD42b Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
FACS, WB, IHC, ELISA, ICC, Neut
Validierungen
- (5)
Kat. Nr.
ABIN5684108
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7440512
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS, WB, ELISA, IP, ICC
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN2752000
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene CD42b ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6973599
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960662
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4882209
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CD42b Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274755
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355497
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355499
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CD42b Produkten
: "GPIbα shedding in platelets is controlled by strict intracellular containment of both enzyme and substrate." in: Journal of thrombosis and haemostasis : JTH, (2023) (PubMed).: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." in: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).
: "Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation." in: Haematologica, (2019) (PubMed).
: "Temperature effects on the activity, shape, and storage of platelets from 13-lined ground squirrels." in: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Vol. 187, Issue 5-6, pp. 815-825, (2017) (PubMed).
: "Nanoparticle biointerfacing by platelet membrane cloaking." in: Nature, Vol. 526, Issue 7571, pp. 118-21, (2015) (PubMed).
: "A dominant-negative GFI1B mutation in the gray platelet syndrome. ..." in: The New England journal of medicine, Vol. 370, Issue 3, pp. 245-53, (2014) (PubMed).
: "Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylation." in: The Journal of experimental medicine, (2014) (PubMed).
: "Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse." in: Journal of thrombosis and haemostasis : JTH, Vol. 10, Issue 11, pp. 2344-53, (2014) (PubMed).
: "The collagen-binding integrin α2β1 is a novel interaction partner of the Trimeresurus flavoviridis venom protein flavocetin-A." in: The Journal of biological chemistry, Vol. 288, Issue 2, pp. 947-55, (2013) (PubMed).
: "Expression of megakaryocytic and myeloid markers in blasts of transient abnormal myelopoiesis in a stillbirth with Down syndrome: report of histopathological findings of an autopsy case." in: Human pathology, Vol. 42, Issue 1, pp. 141-5, (2010) (PubMed).
Synonyme und alternative Namen zu CD42b
glycoprotein Ib platelet alpha subunit (GP1BA), glycoprotein Ib (platelet), alpha polypeptide (GP1BA), glycoprotein Ib platelet alpha subunit (Gp1ba), glycoprotein 1b, alpha polypeptide (Gp1ba), BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GP1BA, GPIbA, GPIba, GPIbalpha, VWDPBezeichner auf Proteinebene für CD42b
- GP-Ib alpha
- antigen CD42b-alpha
- platelet glycoprotein Ib alpha chain
- platelet membrane glycoprotein 1b-alpha subunit
- glycoprotein Ib (platelet), alpha polypeptide
- platelet glycoprotein Ib alpha polypeptide
- GPIb-alpha
- GPIbA
- glycoprotein Ibalpha
- glycoprotein 1b, alpha polypeptide
- platelet glycoprotein Ib alpha chain-like
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