CD46 Produkte
(CD46)
Kategorien
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].
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Ausgewählte CD46 Kategorien
CD46 Antikörper
High quality antibodies with extensive validation data.
CD46 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD46 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CD46 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, ELISA, IHC, ICC, Neut
Validierungen
- (6)
Kat. Nr.
ABIN7193208
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC
Validierungen
- (6)
Kat. Nr.
ABIN1512715
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, ELISA, IF, IHC
Validierungen
- (7)
Kat. Nr.
ABIN3030405
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene CD46 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6954523
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965590
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962394
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CD46 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274180
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274175
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Dog
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7274176
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CD46 Produkten
: "The Role of Taste Receptor mTAS1R3 in Chemical Communication of Gametes." in: International journal of molecular sciences, Vol. 21, Issue 7, (2020) (PubMed).: "An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor." in: Cell, Vol. 174, Issue 5, pp. 1158-1171.e19, (2019) (PubMed).
: "Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions." in: Nature communications, Vol. 10, Issue 1, pp. 741, (2019) (PubMed).
: "CD46 facilitates entry and dissemination of human cytomegalovirus." in: Nature communications, Vol. 10, Issue 1, pp. 2699, (2019) (PubMed).
: "Alternative pathway activation due to low level of complement factor H in primary antiphospholipid syndrome." in: Thrombosis research, Vol. 164, pp. 63-68, (2018) (PubMed).
: "Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus." in: European journal of immunology, Vol. 47, Issue 7, pp. 1200-1210, (2017) (PubMed).
: "Preclinical safety, pharmacokinetics, pharmacodynamics, and biodistribution studies with Ad35K++ protein: a novel rituximab cotherapeutic." in: Molecular therapy. Methods & clinical development, Vol. 5, pp. 16013, (2016) (PubMed).
: "Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus." in: Cardiovascular diabetology, Vol. 15, Issue 1, pp. 152, (2016) (PubMed).
: "Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors." in: Journal of virology, Vol. 89, Issue 3, pp. 1512-22, (2015) (PubMed).
: "Expression of membrane complement regulators, CD46, CD55 and CD59, in mesothelial cells of patients on peritoneal dialysis therapy." in: Molecular immunology, Vol. 65, Issue 2, pp. 302-9, (2015) (PubMed).
Synonyme und alternative Namen zu CD46
CD46 molecule (CD46), CD46 antigen, complement regulatory protein (Cd46), CD46 molecule (Cd46), CD46 molecule, complement regulatory protein (CD46), membrane cofactor protein-like (LOC100341359), membrane cofactor protein-like (LOC103789310), AHUS2, CD46, MCP, Mcp, MIC10, TLX, TRA2.10Bezeichner auf Proteinebene für CD46
- CD46 antigen, complement regulatory protein
- antigen identified by monoclonal antibody TRA-2-10
- complement membrane cofactor protein
- measles virus receptor
- membrane cofactor protein
- membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
- trophoblast leucocyte common antigen
- trophoblast leukocyte common antigen
- trophoblast-lymphocyte cross-reactive antigen
- brain microvascular membrane cofactor
- membrane cofactor protein(GMP1-full)
- CD46 molecule
- Membrane cofactor protein
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