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CD53 Produkte

(CD53)

Kategorien

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

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Ausgewählte CD53 Kategorien

CD53 Antikörper

High quality antibodies with extensive validation data.

CD53 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD53 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CD53 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation FACS, WB, ELISA, IHC, ICC, Neut
Validierungen
  • (7)
Kat. Nr. ABIN7193233
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, WB, ELISA, IHC, ICC, Neut
Validierungen
  • (5)
Kat. Nr. ABIN7193232
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS
Validierungen
  • (5)
  • (3)
Kat. Nr. ABIN192139
Menge 100 tests
Datenblatt Datenblatt

Empfohlene CD53 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730119
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CD53 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1329990
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1348669
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320175
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CD53 Produkten

Zuidscherwoude, Göttfert, Dunlock, Figdor, van den Bogaart, van Spriel: "The tetraspanin web revisited by super-resolution microscopy." in: Scientific reports, Vol. 5, pp. 12201, (2015) (PubMed).

Schatzlmaier, Supper, Göschl, Zwirzitz, Eckerstorfer, Ellmeier, Huppa, Stockinger: "Rapid multiplex analysis of lipid raft components with single-cell resolution." in: Science signaling, Vol. 8, Issue 395, pp. rs11, (2015) (PubMed).

Kim, Yoon, Kim, Yook, Kim, Kim, Lee, Paik: "LPS-induced CD53 expression: a protection mechanism against oxidative and radiation stress." in: Molecules and cells, Vol. 17, Issue 1, pp. 125-31, (2004) (PubMed).

Yunta, Rodríguez-Barbero, Arévalo, López-Novoa, Lazo: "Induction of DNA synthesis by ligation of the CD53 tetraspanin antigen in primary cultures of mesangial cells." in: Kidney international, Vol. 63, Issue 2, pp. 534-42, (2003) (PubMed).

Puls, Hogquist, Reilly, Wright: "CD53, a thymocyte selection marker whose induction requires a lower affinity TCR-MHC interaction than CD69, but is up-regulated with slower kinetics." in: International immunology, Vol. 14, Issue 3, pp. 249-58, (2002) (PubMed).

Szöllósi, Horejsí, Bene, Angelisová, Damjanovich: "Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2939-46, (1996) (PubMed).

Crook, Hunt: "Enrichment of early fetal-liver hemopoietic stem cells of the rat using monoclonal antibodies against the transferrin receptor, Thy-1, and MRC-OX82." in: Developmental immunology, Vol. 4, Issue 4, pp. 235-46, (1996) (PubMed).

Carmo, Wright: "Association of the transmembrane 4 superfamily molecule CD53 with a tyrosine phosphatase activity." in: European journal of immunology, Vol. 25, Issue 7, pp. 2090-5, (1995) (PubMed).

Tomlinson, Hanke, Hughes, Barclay, Scholl, Hünig, Wright: "Characterization of mouse CD53: epitope mapping, cellular distribution and induction by T cell receptor engagement during repertoire selection." in: European journal of immunology, Vol. 25, Issue 8, pp. 2201-5, (1995) (PubMed).

Olweus, Lund-Johansen, Terstappen: "CD64/Fc gamma RI is a granulo-monocytic lineage marker on CD34+ hematopoietic progenitor cells." in: Blood, Vol. 85, Issue 9, pp. 2402-13, (1995) (PubMed).

Synonyme und alternative Namen zu CD53

CD53 antigen (Cd53), CD53 molecule (CD53), Cd53 molecule (Cd53), AI323659, MOX44, Ox-44, OX44, Tspan25, TSPAN25

Bezeichner auf Proteinebene für CD53

  • cell surface glycoprotein CD53
  • leukocyte surface antigen CD53
  • CD53 antigen
  • CD53 glycoprotein
  • CD53 tetraspan antigen
  • antigen MOX44 identified by monoclonal antibody MRC-OX44
  • cell surface antigen
  • tetraspanin-25
  • transmembrane glycoprotein
  • tspan-25
  • leukocyte antigen MRC OX-44
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