MTHFD1 Antikörper (AA 535-562)

Produktnummer ABIN389285

Produktdetails anti-MTHFD1 Antikörper

Target: MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

Bindungsspezifität: AA 535-562

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTHFD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MTHFD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-562 amino acids from the Central region of human MTHFD1.

Klon: RB19391

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MTHFD1

Target: MTHFD1 (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase (MTHFD1))

Andere Bezeichnung: MTHFD1 (MTHFD1 Produkte)

Synonyme: MTHFC antikoerper, MTHFD antikoerper, Tb07.27M11.970 antikoerper, Dcs antikoerper, E430024A07Rik antikoerper, Mthfd antikoerper, GB13160 antikoerper, cb325 antikoerper, fc29f07 antikoerper, mthfd1 antikoerper, wu:fc29f07 antikoerper, zgc:55597 antikoerper, methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 antikoerper, C-1-tetrahydrofolate synthase, cytoplasmic antikoerper, putative C-1-tetrahydrofolate synthase, cytoplasmic antikoerper, putative C-1-tetrahydrofolate synthase,cytoplasmic antikoerper, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like antikoerper, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase antikoerper, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b antikoerper, c-1-tetrahydrofolate synthase, cytoplasmic antikoerper, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase L homeolog antikoerper, methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase antikoerper, MTHFD1 antikoerper, Mthfd1 antikoerper, Tc00.1047053509509.20 antikoerper, Tc00.1047053511741.50 antikoerper, Tc00.1047053511517.60 antikoerper, Tc00.1047053508207.240 antikoerper, Tb927.7.1600 antikoerper, LINJ_26_0310 antikoerper, LBRM_26_0350 antikoerper, LMJF_26_0320 antikoerper, mthfd1l antikoerper, LOC550749 antikoerper, mthfd1b antikoerper, Tsp_00651 antikoerper, mthfd1.L antikoerper, mthfd1 antikoerper, LOC589933 antikoerper, LOC100634307 antikoerper

Hintergrund: MTHFD1 is a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

Molekulargewicht: 101559

Gen-ID: 4522

NCBI Accession: NP_005947

UniProt: P11586

Pathways: Methionine Biosynthetic Process