CACNB4 Antikörper (C-Term, Internal Region)

Produktnummer ABIN375181

Produktdetails anti-CACNB4 Antikörper

Target: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Bindungsspezifität: C-Term, Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CACNB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to CACNB4.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-DYPDSYQDTYKPH, from the internal region (near the C Terminus) of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/4000. Western Blot: 0.2 - 0.6 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CACNB4

Target: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Andere Bezeichnung: CACNB4 (CACNB4 Produkte)

Synonyme: CAB4 antikoerper, CACNLB4 antikoerper, EA5 antikoerper, EIG9 antikoerper, EJM antikoerper, EJM4 antikoerper, EJM6 antikoerper, 3110038O15Rik antikoerper, Cchb4 antikoerper, lethargic antikoerper, lh antikoerper, CACNB4 antikoerper, cacnb4.2 antikoerper, calcium voltage-gated channel auxiliary subunit beta 4 antikoerper, calcium channel, voltage-dependent, beta 4 subunit antikoerper, calcium channel, voltage-dependent, beta 4a subunit antikoerper, CACNB4 antikoerper, Cacnb4 antikoerper, cacnb4.1 antikoerper, cacnb4 antikoerper, cacnb4a antikoerper

Hintergrund: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. CACNB4 is expressed predominantly in the cerebellum and kidney. Defects in CACNB4 are a cause of idiopathic generalized epilepsy (IGE). IGE is characterized by recurrent generalized seizures. Defects in CACNB4 are also a cause of juvenile myoclonic epilepsy (JME). JME is a common epileptic syndrome characterized by afebrile seizures, onset in adolescence (rather than in childhood) and myoclonic jerks.Synonyms: CAB4, CACNLB4, Calcium channel voltage-dependent subunit beta 4, Voltage-dependent L-type calcium channel subunit beta-4

Gen-ID: 785

NCBI Accession: NP_000717

UniProt: O00305

Pathways: cAMP Metabolic Process, Skeletal Muscle Fiber Development