CACNB4 Antikörper (Middle Region)
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- Target Alle CACNB4 Antikörper anzeigen
- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CACNB4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- FDGRISITRV TADISLAKRS VLNNPSKRAI IERSNTRISS LAEVQSEIER IF
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CACNB4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CACNB4
- Top Product
- Discover our top product CACNB4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 458 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
- Andere Bezeichnung
- CACNB4 (CACNB4 Produkte)
- Hintergrund
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CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).
Alias Symbols: EA5, EJM, CAB4, EIG9, EJM4, EJM6, CACNLB4
Protein Interaction Partner: CBX3, FASLG, REM1, MED31, TBL3, CACNA1A, PTN,
Protein Size: 458 - Molekulargewicht
- 50 kDa
- Gen-ID
- 785
- NCBI Accession
- NM_000726, NP_001139270
- UniProt
- A7BJ74
- Pathways
- cAMP Metabolic Process, Skeletal Muscle Fiber Development
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