CACNB4 Antikörper (Middle Region)

Produktnummer ABIN2774681

Der Kaninchen Polyklonal anti-CACNB4 Antikörper (ABIN2774681) detektiert spezifisch CACNB4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Hund und Pferd.

Kurzübersicht für CACNB4 Antikörper (Middle Region) (ABIN2774681)

Target: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CACNB4 Antikörper

Bindungsspezifität: Middle Region

Sequenz: FDGRISITRV TADISLAKRS VLNNPSKRAI IERSNTRISS LAEVQSEIER IF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CACNB4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CACNB4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 458 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CACNB4

Target: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Andere Bezeichnung: CACNB4

Hintergrund: CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).
Alias Symbols: EA5, EJM, CAB4, EIG9, EJM4, EJM6, CACNLB4
Protein Interaction Partner: CBX3, FASLG, REM1, MED31, TBL3, CACNA1A, PTN,
Protein Size: 458

Molekulargewicht: 50 kDa

Gen-ID: 785

NCBI Accession: NM_000726, NP_001139270

UniProt: A7BJ74

Pathways: cAMP Metabolic Process, Skeletal Muscle Fiber Development