Aromatase Antikörper (Internal Region)

Produktnummer ABIN374919

Produktdetails anti-Aromatase Antikörper

Target: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Aromatase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequenz: C-HDLSLHPDET KN

Spezifität: This antibody is expected to recognise both reported isoforms (NP_000094.2 and NP_112503.1), which are identical

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Peptide with sequence from the internal region of Human CYP19A1.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/128000. Western blot: 0.1-0.3 μg/mL. Detects a band of approx. 50-55 kDa in Human Placenta lysates. Immunohistochemistry on Paraffin Sections: 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Aromatase

Target: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Andere Bezeichnung: Aromatase (CYP19A1 Produkte)

Synonyme: ARO antikoerper, ARO1 antikoerper, CPV1 antikoerper, CYAR antikoerper, CYP19 antikoerper, CYPXIX antikoerper, P-450AROM antikoerper, Aromatase antikoerper, Cyp19 antikoerper, Cyp19a antikoerper, p450arom antikoerper, P450 arom antikoerper, aro antikoerper, cyp19 antikoerper, cyp19a antikoerper, p450arom-A antikoerper, P450AROM antikoerper, Ar antikoerper, ArKO antikoerper, Int-5 antikoerper, Int5 antikoerper, CYP19P1 antikoerper, CYP19A1 antikoerper, CYP19a1 antikoerper, P450aromA antikoerper, ar1 antikoerper, cypXIX antikoerper, etID309862.18 antikoerper, zgc:136541 antikoerper, AroB antikoerper, CYP19a2 antikoerper, P450aromB antikoerper, cyp19b antikoerper, zgc:92614 antikoerper, cyp19a1 antikoerper, cytochrome P450 family 19 subfamily A member 1 antikoerper, cytochrome P450, family 19, subfamily a, polypeptide 1 antikoerper, cytochrome P450 family 19 subfamily A member 1 L homeolog antikoerper, aromatase antikoerper, cytochrome P450 aromatase antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1 antikoerper, cytochrome P450 19A1 antikoerper, cytochrome P450, family 17, subfamily A, polypeptide 1 antikoerper, cytochrome P450, family 19 antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1a antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1b antikoerper, cytochrome P450 19A1-like antikoerper, CYP19A1 antikoerper, Cyp19a1 antikoerper, cyp19a1.L antikoerper, SAV_2383 antikoerper, pfcyp19b-tstr antikoerper, CYP19 antikoerper, cyp19a1a antikoerper, cyp19a1b antikoerper, LOC101174651 antikoerper

Hintergrund: Aromatase is a key enzyme in steroidogenesis and plays an important role in sexual differentiation, oestrogen biosynthesis, fertility and carcinogenesis. It is highly conserved amongst mammals, and is highly expressed in placental tissue. Many environmental chemicals may influence aromatase activity and thereby disrupt endocrine function.Synonyms: ARO1, CYAR, CYP19, CYP19A1, CYPXIX, Cytochrome P450 19A1, Estrogen synthetase, P450AROM

Molekulargewicht: 57.9kDa (NP_000094.2 and NP_112503.1).

Gen-ID: 1588, 9606

UniProt: P11511

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis