Aromatase Antikörper (AA 1-180)

Produktnummer ABIN6139316

Produktdetails anti-Aromatase Antikörper

Target: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Bindungsspezifität: AA 1-180

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aromatase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MVLEMLNPIH YNITSIVPEA MPAATMPVLL LTGLFLLVWN YEGTSSIPGP GYCMGIGPLI SHGRFLWMGI GSACNYYNRV YGEFMRVWIS GEETLIISKS SSMFHIMKHN HYSSRFGSKL GLQCIGMHEK GIIFNNNPEL WKTTRPFFMK ALSGPGLVRM VTVCAESLKT HLDRLEEVTN

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human Aromatase (CYP19A1) (NP_000094.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Aromatase

Target: Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))

Andere Bezeichnung: CYP19A1 (CYP19A1 Produkte)

Synonyme: ARO antikoerper, ARO1 antikoerper, CPV1 antikoerper, CYAR antikoerper, CYP19 antikoerper, CYPXIX antikoerper, P-450AROM antikoerper, Aromatase antikoerper, Cyp19 antikoerper, Cyp19a antikoerper, p450arom antikoerper, P450 arom antikoerper, aro antikoerper, cyp19 antikoerper, cyp19a antikoerper, p450arom-A antikoerper, P450AROM antikoerper, Ar antikoerper, ArKO antikoerper, Int-5 antikoerper, Int5 antikoerper, CYP19P1 antikoerper, CYP19A1 antikoerper, CYP19a1 antikoerper, P450aromA antikoerper, ar1 antikoerper, cypXIX antikoerper, etID309862.18 antikoerper, zgc:136541 antikoerper, AroB antikoerper, CYP19a2 antikoerper, P450aromB antikoerper, cyp19b antikoerper, zgc:92614 antikoerper, cyp19a1 antikoerper, cytochrome P450 family 19 subfamily A member 1 antikoerper, cytochrome P450, family 19, subfamily a, polypeptide 1 antikoerper, cytochrome P450 family 19 subfamily A member 1 L homeolog antikoerper, aromatase antikoerper, cytochrome P450 aromatase antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1 antikoerper, cytochrome P450 19A1 antikoerper, cytochrome P450, family 17, subfamily A, polypeptide 1 antikoerper, cytochrome P450, family 19 antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1a antikoerper, cytochrome P450, family 19, subfamily A, polypeptide 1b antikoerper, cytochrome P450 19A1-like antikoerper, CYP19A1 antikoerper, Cyp19a1 antikoerper, cyp19a1.L antikoerper, SAV_2383 antikoerper, pfcyp19b-tstr antikoerper, CYP19 antikoerper, cyp19a1a antikoerper, cyp19a1b antikoerper, LOC101174651 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.,CYP19A1,ARO,ARO1,CPV1,CYAR,CYP19,CYPXIX,P-450AROM,aromatase,Aromatase,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,CYP19A1

Molekulargewicht: 24 kDa/57 kDa

Gen-ID: 1588

UniProt: P11511

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis