FGF21 Antikörper (Internal Region)

Produktnummer ABIN374880

Produktdetails anti-FGF21 Antikörper

Target: FGF21 (Fibroblast Growth Factor 21 (FGF21))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser FGF21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CQRPDGALYG SLH

Spezifität: This antibody detects FGF21.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_061986.1.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: limit dilution 1: 2000. Western blot: 1-3 μg/mL. Approx 22 kDa band observed in Human Liver lysates (calculatedMW of 22.2 kDa according to NP_061986.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-FGF21 Antikörper (ABIN374880)

Cyphert, Ge, Kohan, Salati, Zhang, Hillgartner: "Activation of the farnesoid X receptor induces hepatic expression and secretion of fibroblast growth factor 21." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25123-38, (2012) (PubMed).

Details zu FGF21

Target: FGF21 (Fibroblast Growth Factor 21 (FGF21))

Andere Bezeichnung: FGF21 (FGF21 Produkte)

Synonyme: FGF21 antikoerper, fibroblast growth factor 21 antikoerper, FGF21 antikoerper, fgf21 antikoerper, Fgf21 antikoerper

Hintergrund: FGF21 is a growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes.Synonyms: FGF-21, Fibroblast growth factor 21

Gen-ID: 26291, 9606

UniProt: Q9NSA1

Pathways: RTK Signalweg