PSME1 Antikörper (C-Term, Isoform 1)

Produktnummer ABIN374820

Produktdetails anti-PSME1 Antikörper

Target: PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))

Bindungsspezifität: C-Term, Isoform 1

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PSME1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody is expected to recognise isoform 1 (NP_006254.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-KNFEKLKKPRGETK, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit: 1/64000. Western Blot: 0.3-1 μg/mL. Approx 30 kDa band observed in Human Lymph Node, Spleen, Tonsil and Peripheral BloodMononuceocyte lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PSME1

Target: PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))

Andere Bezeichnung: PSME1 (PSME1 Produkte)

Synonyme: fk89d05 antikoerper, wu:fk89d05 antikoerper, IFI5111 antikoerper, PA28A antikoerper, PA28alpha antikoerper, REGalpha antikoerper, AW413925 antikoerper, PA28a antikoerper, proteasome activator subunit 1 antikoerper, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antikoerper, psme1 antikoerper, PSME1 antikoerper, Psme1 antikoerper

Hintergrund: PSME1 is implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.Synonyms: 11S regulator complex subunit alpha, Activator of multicatalytic protease subunit 1, IFI5111, IGUP I-5111, Interferon gamma up-regulated I-5111 protein, PA28a, PA28alpha, PSME-1, Proteasome activator 28 subunit alpha, Proteasome activator complex subunit 1, REG-alpha

Gen-ID: 5720

NCBI Accession: NP_006254

UniProt: Q06323

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA