CYP17A1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Peptide ELISA: 1/64000. Western Blot: 0.1 - 0.3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
cyp17 antikoerper, CYPXVII antikoerper, P450c17 antikoerper, cyp17a1 antikoerper, P450-C17 antikoerper, wu:fi13g04 antikoerper, wu:fi17b11 antikoerper, wu:fi31c08 antikoerper, zgc:136516 antikoerper, zgc:66494 antikoerper, P45017A1 antikoerper, CYP17 antikoerper, CPT7 antikoerper, P450C17 antikoerper, S17AH antikoerper, Cyp17 antikoerper, p450c17 antikoerper, cytochrome P450 17A1 antikoerper, cytochrome P450, family 17, subfamily A, polypeptide 1 antikoerper, steroidogenic cytochrome P450 17-hydroxylase/lyase antikoerper, cytochrome P450 family 17 subfamily A member 1 L homeolog antikoerper, cytochrome P450 family 17 subfamily A member 1 antikoerper, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase antikoerper, cytochrome P450, family 17, subfamily a, polypeptide 1 antikoerper, cytochrome P450c17 antikoerper, CpipJ_CPIJ010537 antikoerper, CpipJ_CPIJ010543 antikoerper, PTRG_02047 antikoerper, cyp17a1 antikoerper, cyp17 antikoerper, cyp17a1.L antikoerper, CYP17A1 antikoerper, Cyp17a1 antikoerper
Hintergrund
Cytochrome P450 17A1 (CYP17A1) belongs to the cytochrome P450 family, it plays a role in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. CYP17A1 also catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. CYP17A1 is involved in sexual development during fetal life and at puberty. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5). AH5 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol.Synonyms: 20 lyase, CYP17, CYPXVII, Cytochrome P450 17A1, P450-C17, P450c17, S17AH, Steroid 17-alpha-hydroxylase/17, Steroid 17-alpha-monooxygenase