CYP17A1 Antikörper (Center)
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- Target Alle CYP17A1 Antikörper anzeigen
- CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
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Bindungsspezifität
- Center
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP17A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Schimpanse
- Kreuzreaktivität (Details)
- Chimpanzee (100 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to CYP17A1 (cytochrome P450, family 17, subfamily A, polypeptide 1)
CYP17A1 antibody [N1C2] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human CYP17A1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product CYP17A1 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference Western blot 1:500-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:20000*
- Kommentare
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Positive Control: NIH-3T3 , C2C12 , MCF-7 , HepG2
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.65 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
- Andere Bezeichnung
- CYP17A1 (CYP17A1 Produkte)
- Synonyme
- cyp17 antikoerper, CYPXVII antikoerper, P450c17 antikoerper, cyp17a1 antikoerper, P450-C17 antikoerper, wu:fi13g04 antikoerper, wu:fi17b11 antikoerper, wu:fi31c08 antikoerper, zgc:136516 antikoerper, zgc:66494 antikoerper, P45017A1 antikoerper, CYP17 antikoerper, CPT7 antikoerper, P450C17 antikoerper, S17AH antikoerper, Cyp17 antikoerper, p450c17 antikoerper, cytochrome P450 17A1 antikoerper, cytochrome P450, family 17, subfamily A, polypeptide 1 antikoerper, steroidogenic cytochrome P450 17-hydroxylase/lyase antikoerper, cytochrome P450 family 17 subfamily A member 1 L homeolog antikoerper, cytochrome P450 family 17 subfamily A member 1 antikoerper, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase antikoerper, cytochrome P450, family 17, subfamily a, polypeptide 1 antikoerper, cytochrome P450c17 antikoerper, CpipJ_CPIJ010537 antikoerper, CpipJ_CPIJ010543 antikoerper, PTRG_02047 antikoerper, cyp17a1 antikoerper, cyp17 antikoerper, cyp17a1.L antikoerper, CYP17A1 antikoerper, Cyp17a1 antikoerper
- Hintergrund
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
Cellular Localization: Membrane , Membrane, Single-pass membrane protein , Membrane , Membrane - Molekulargewicht
- 57 kDa
- Gen-ID
- 1586
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
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