COMT Antikörper (N-Term)

Produktnummer ABIN374503

Produktdetails anti-COMT Antikörper

Target: COMT (Catechol-O-Methyltransferase (COMT))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser COMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody is expected to recognise both reported isoforms. Variants (NP_000745.1, NP_001128633.1 and NP_001128634.1) encode the same isoform.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat and Canine (Dog).
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence GDTKEQRILNHVLQC, from the N-Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit Dilution: 1/4000. Western Blot: 0.3-1.0 μg/mL. Approx 26 kDa plus 26 kDa bands observed in Human Testislysates (calculated MW of 30.6 kDa according to NP_000745.1 and of 24.6 kDa according toNP_009294.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu COMT

Target: COMT (Catechol-O-Methyltransferase (COMT))

Andere Bezeichnung: COMT (COMT Produkte)

Synonyme: Comt1 antikoerper, D16Wsu103e antikoerper, D330014B15Rik antikoerper, COMT antikoerper, mb-comt antikoerper, s-comt antikoerper, comt antikoerper, MGC154444 antikoerper, zgc:114157 antikoerper, si:dkey-13a21.15 antikoerper, zK13A21.15 antikoerper, zgc:162236 antikoerper, catechol-O-methyltransferase antikoerper, microRNA 4761 antikoerper, catechol-O-methyltransferase S homeolog antikoerper, methyltransferase antikoerper, catechol-o-methyltransferase antikoerper, catechol-O-methyltransferase a antikoerper, catechol-O-methyltransferase b antikoerper, catechol O-methyltransferase antikoerper, COMT antikoerper, Comt antikoerper, MIR4761 antikoerper, comt antikoerper, comt.2 antikoerper, comt.S antikoerper, Rv1703c antikoerper, Mb1729c antikoerper, comta antikoerper, comtb antikoerper, LOC100354142 antikoerper

Hintergrund: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease.Synonyms: Catechol O-methyltransferase

Gen-ID: 1312, 9606

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interaktom