RNF2 Antikörper (C-Term)

Produktnummer ABIN374300

Produktdetails anti-RNF2 Antikörper

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser RNF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-PMELYYAPTK EHK

Spezifität: This antibody detects RNF2 at C-term.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Dog, Cow.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide from C-Terminus of Human RNF2. Genename: RNF2

Anwendungsinformationen

Applikationshinweise: ELISA (1/4000). Western blot (0.3-1 μg/mL). Immunohistochemistry on Paraffin Sections (3.75 μg/mL). This antibody validated for use in Immunohistochemistry on a panel of 21 formalin-fixed,paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0citrate buffer. After incubation with the primary antibody, slides were incubated withbiotinylated secondary antibody, followed by alkaline phosphatase-streptavidin andchromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Andere Bezeichnung: RNF2 (RNF2 Produkte)

Synonyme: BAP-1 antikoerper, BAP1 antikoerper, DING antikoerper, HIPI3 antikoerper, RING1B antikoerper, RING2 antikoerper, AI326319 antikoerper, AI450156 antikoerper, AU019207 antikoerper, Ring1B antikoerper, dinG antikoerper, fa19h05 antikoerper, ring1b antikoerper, wu:fa19h05 antikoerper, wz4556 antikoerper, bap-1 antikoerper, bap1 antikoerper, ding antikoerper, hipi3 antikoerper, ring2 antikoerper, ring finger protein 2 antikoerper, ring finger protein 2 L homeolog antikoerper, RNF2 antikoerper, Rnf2 antikoerper, rnf2 antikoerper, rnf2.L antikoerper

Hintergrund: RING1B (also known as BAP1, DING, Polycomb-M33 interacting protein Ring1B, Ring finger protein 1b, Ring finger protein 2 and RNF2) is one of the PcG proteins. The polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), a ubiquitin-conjugating enzyme that possesses ubiquitin ligase activity.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B

Gen-ID: 6045

NCBI Accession: NP_009143

UniProt: Q99496