KLF1 Antikörper (N-Term)

Produktnummer ABIN374197

Produktdetails anti-KLF1 Antikörper

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Schwein, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser KLF1 Antikörper ist unkonjugiert

Applikation: Chromatin Immunoprecipitation (ChIP)

Sequenz: ATAETALPSI STLT-C

Spezifität: This antibody detects Krueppel-like factor 1 (KLF1) at N-term.

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog), Pig, Bovine.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Synthetic peptide from the N-Terminus of the protein sequence according to NP_006554.1 Genename: KLF1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 32000. ABIN374197 has been successfully used in ChiP, see Hou et al. , PNAS, 2008. ChIP: Please see: Hou C. et al. CTCF-dependent enhancer-blocking by alternative chromatinloop formation. Proc Natl Acad Sci U S A.2008 Dec 23,105(51): 20398-403. Epub 2008 Dec12.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KLF1

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Andere Bezeichnung: Krueppel-Like Factor 1 (KLF1) (KLF1 Produkte)

Synonyme: KLF1 antikoerper, EKLF antikoerper, HBFQTL6 antikoerper, INLU antikoerper, Eklf antikoerper, Nan antikoerper, Kruppel-like factor 1 (erythroid) antikoerper, Kruppel like factor 1 antikoerper, KLF-4 antikoerper, KLF1 antikoerper, Klf1 antikoerper

Hintergrund: EKLF / KLF1 is an essential transcriptional activator that directs high-level expression of the adult beta-globin promoter by binding to its CACCC element. Probably serves as a general switch factor for erythroid development. Human EKLF is expressed in bone marrow and erythroleukemic cells lines but not in myeloid or lymphoid cell lines.Synonyms: EKLF, Erythroid krueppel-like transcription factor, Erythroid transcription factor, KLF-1, KLF1, Krueppel-like factor 1

Gen-ID: 10661

NCBI Accession: NP_006554

UniProt: Q13351