KLF1 Antikörper

Produktnummer ABIN7248551

Produktdetails anti-KLF1 Antikörper

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human KLF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100, ELISA 1:2000-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KLF1

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Andere Bezeichnung: KLF1 (KLF1 Produkte)

Synonyme: KLF1 antikoerper, EKLF antikoerper, HBFQTL6 antikoerper, INLU antikoerper, Eklf antikoerper, Nan antikoerper, Kruppel-like factor 1 (erythroid) antikoerper, Kruppel like factor 1 antikoerper, KLF-4 antikoerper, KLF1 antikoerper, Klf1 antikoerper

Hintergrund: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

UniProt: Q13351