SCNN1G Antikörper (C-Term)

Produktnummer ABIN372870

Produktdetails anti-SCNN1G Antikörper

Target: SCNN1G (Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCNN1G Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detetcs Human SCNN1G at C-term.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide corresponding to C-terminal residues of Human SCNN1G (Amiloride- sensitive sodium channel gamma-subunit).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 5 μg/mL. Western blot: 1 μg/mL. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.01 % Sodium Azide and 50 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu SCNN1G

Target: SCNN1G (Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G))

Andere Bezeichnung: ENAC gamma / SCNN1G (SCNN1G Produkte)

Synonyme: ENaC antikoerper, BESC3 antikoerper, ENaCg antikoerper, ENaCgamma antikoerper, PHA1 antikoerper, SCNEG antikoerper, scnn1g antikoerper, MGC81424 antikoerper, SCNN1G antikoerper, enacg antikoerper, gammaxENaC-A antikoerper, pha1 antikoerper, [g]ENaC antikoerper, GAMMA-ENAC antikoerper, gamma XENaC antikoerper, gamma-ENaC antikoerper, gamma2xENaC-A antikoerper, scneg antikoerper, sodium channel epithelial 1 gamma subunit antikoerper, sodium channel, nonvoltage-gated 1, gamma antikoerper, sodium channel, non voltage gated 1 gamma subunit L homeolog antikoerper, sodium channel, nonvoltage-gated 1 gamma antikoerper, sodium channel, non voltage gated 1 gamma subunit S homeolog antikoerper, Scnn1g antikoerper, SCNN1G antikoerper, scnn1g antikoerper, scnn1g.L antikoerper, scnn1g.S antikoerper

Hintergrund: Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel's syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).Synonyms: Amiloride-sensitive sodium channel subunit gamma, ENaCG, Epithelial Na(+) channel subunit gamma, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG

Gen-ID: 6340

NCBI Accession: NP_001030

UniProt: P51170