SCNN1G Antikörper (AA 80-401)

Produktnummer ABIN7427612

Produktdetails anti-SCNN1G Antikörper

Target: SCNN1G (Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G))

Bindungsspezifität: AA 80-401

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SCNN1G Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Monoclonal Antibody to Amiloride Sensitive Sodium Channel Subunit Gamma (SCNN1g)

Spezifität: The antibody is a mouse monoclonal antibody raised against SCNN1g. It has been selected for its ability to recognize SCNN1g in immunohistochemical staining and western blotting.

Aufreinigung: Protein A + Protein G affinity chromatography

Immunogen: Recombinant Amiloride Sensitive Sodium Channel Subunit Gamma (SCNN1g) corresdonding to Thr80~Thr401 with N-terminal His Tag

Klon: C1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Western blotting: 0.5-2 μg/mL

Immunohistochemistry: 5-20 μg/mL

Immunocytochemistry: 5-20 μg/mL

Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Referenzen für anti-SCNN1G Antikörper (ABIN7427612)

Sudarikova, Bychkov, Kulbatskii, Chubinskiy-Nadezhdin, Shlepova, Shulepko, Koshelev, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer." in: Frontiers in oncology, Vol. 12, pp. 904742, (2022) (PubMed).

Bychkov, Kirichenko, Shulepko, Mikhaylova, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." in: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).

Details zu SCNN1G

Target: SCNN1G (Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G))

Andere Bezeichnung: Amiloride Sensitive Sodium Channel Subunit Gamma (SCNN1G Produkte)

Synonyme: ENaC antikoerper, BESC3 antikoerper, ENaCg antikoerper, ENaCgamma antikoerper, PHA1 antikoerper, SCNEG antikoerper, scnn1g antikoerper, MGC81424 antikoerper, SCNN1G antikoerper, enacg antikoerper, gammaxENaC-A antikoerper, pha1 antikoerper, [g]ENaC antikoerper, GAMMA-ENAC antikoerper, gamma XENaC antikoerper, gamma-ENaC antikoerper, gamma2xENaC-A antikoerper, scneg antikoerper, sodium channel epithelial 1 gamma subunit antikoerper, sodium channel, nonvoltage-gated 1, gamma antikoerper, sodium channel, non voltage gated 1 gamma subunit L homeolog antikoerper, sodium channel, nonvoltage-gated 1 gamma antikoerper, sodium channel, non voltage gated 1 gamma subunit S homeolog antikoerper, Scnn1g antikoerper, SCNN1G antikoerper, scnn1g antikoerper, scnn1g.L antikoerper, scnn1g.S antikoerper

Hintergrund: ENaCg, ENaCgamma, PHA1, SCNEG, Sodium Channel,Nonvoltage-Gated 1,Alpha, Epithelial Na(+) channel subunit gamma, Nonvoltage-gated sodium channel 1 subunit gamma