KCNB2
Reaktivität: Ratte, Maus
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 594
Applikationshinweise
Western blot: 1/1000. Immunohistochemistry on Frozen Sections: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody undiluted (in aliquots) at-20 °C.
Target
Kv2.2 (KCNB2)
(Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))
KCNB2 antikoerper, si:ch211-193n21.1 antikoerper, Kv2.2 antikoerper, 9630047L19Rik antikoerper, BB130875 antikoerper, XShab12 antikoerper, kcnb2 antikoerper, KV2.2 antikoerper, potassium voltage-gated channel subfamily B member 2 antikoerper, potassium voltage-gated channel, Shab-related subfamily, member 2 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 2 antikoerper, potassium voltage gated channel, Shab-related subfamily, member 2 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog antikoerper, KCNB2 antikoerper, kcnb2 antikoerper, LOC100051372 antikoerper, Kcnb2 antikoerper, kcnb2.S antikoerper
Hintergrund
Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety of non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993, Yan et al., 2004, Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998, Burger and Ribera, 1996)Synonyms: Potassium voltage-gated channel subfamily B member 2, Voltage-gated potassium channel subunit Kv2.2