Kv2.2 Antikörper (AA 21-120)

Produktnummer ABIN1386740

Produktdetails anti-Kv2.2 Antikörper

Target: Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))

Bindungsspezifität: AA 21-120

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kv2.2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Kv2.2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Kv2.2

Target: Kv2.2 (KCNB2) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 2 (KCNB2))

Andere Bezeichnung: Kv2.2 (KCNB2 Produkte)

Synonyme: KCNB2 antikoerper, si:ch211-193n21.1 antikoerper, Kv2.2 antikoerper, 9630047L19Rik antikoerper, BB130875 antikoerper, XShab12 antikoerper, kcnb2 antikoerper, KV2.2 antikoerper, potassium voltage-gated channel subfamily B member 2 antikoerper, potassium voltage-gated channel, Shab-related subfamily, member 2 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 2 antikoerper, potassium voltage gated channel, Shab-related subfamily, member 2 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 2 S homeolog antikoerper, KCNB2 antikoerper, kcnb2 antikoerper, LOC100051372 antikoerper, Kcnb2 antikoerper, kcnb2.S antikoerper

Hintergrund:

Synonyms: delayed rectier potassium channel protein, KCNB2, KCNB2_HUMAN, potassium channel Kv2.2, potassium voltage gated channel subfamily B member 2, Potassium voltage-gated channel subfamily B member 2, Voltage-gated potassium channel subunit Kv2.2.

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits (KV), which include the KV1, KV2, KV3, KV4 and KV9 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV2.2 is a multi-pass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. Its tail may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.