PAFAH1B1 Antikörper (AA 397-410)

Produktnummer ABIN364420

Produktdetails anti-PAFAH1B1 Antikörper

Target: PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))

Bindungsspezifität: AA 397-410

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Schwein, Kaninchen, Huhn, Xenopus laevis, Fledermaus, Hamster, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PAFAH1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human PAFAH1B1 / LIS1.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Cat, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Xenopus, Salmon, Stickleback, Pufferfish, Zebrafish, Water flea, Tick (100%) Chimpanzee, Drosophila, Ant, Capsaspora (93%) Catfish, Mosquito, Sea anemone, Beetle, Trichoplax (86%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide TGSVDQTVKVWECR from the C-terminus of human PAFAH1B1 / LIS1 (NP_000421.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Cat, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Xenopus, Salmon, Stickleback, Pufferfish, Zebrafish, Water flea, Tick (100%), Chimpanzee, Drosophila, Ant, Capsaspora (93%), Catfish, Mosquito, Sea anemone, Beetle, Trichoplax (86%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000), WB (1 - 3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu PAFAH1B1

Target: PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))

Andere Bezeichnung: PAFAH1B1 / LIS1 (PAFAH1B1 Produkte)

Synonyme: LIS1 antikoerper, LIS2 antikoerper, MDCR antikoerper, MDS antikoerper, PAFAH antikoerper, LIS-1 antikoerper, Lis1 antikoerper, MMS10-U antikoerper, Mdsh antikoerper, Ms10u antikoerper, Pafaha antikoerper, lis2 antikoerper, mdcr antikoerper, mds antikoerper, pafah antikoerper, pafah1b1-b antikoerper, PAFAHA antikoerper, Lis1a antikoerper, platelet activating factor acetylhydrolase 1b regulatory subunit 1 antikoerper, platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 antikoerper, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 antikoerper, platelet activating factor acetylhydrolase 1b regulatory subunit 1 L homeolog antikoerper, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a antikoerper, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b antikoerper, PAFAH1B1 antikoerper, Pafah1b1 antikoerper, pafah1b1.L antikoerper, pafah1b1a antikoerper, pafah1b1b antikoerper

Hintergrund: Name/Gene ID: PAFAH1B1

Synonyms: PAFAH1B1, LIS-1, LIS2, Lissencephaly 1 protein, Lissencephaly-1 protein, MDCR, MDS, PAFAHA, PAF-AH alpha, PAFAH, LIS1, PAF-AH 45 kDa subunit, PAFAH alpha

Gen-ID: 5048

NCBI Accession: NP_000421

UniProt: P43034

Pathways: M Phase, Regulation of Cell Size