MEK1 Antikörper (AA 219-223)
Kurzübersicht für MEK1 Antikörper (AA 219-223) (ABIN362800)
Target
Alle MEK1 (MAP2K1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 219-223
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Spezifität
- The antibody detects endogenous level of total MEK1 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Peptide sequence around AA 219-223 (A-N-S-F-V) derived from Human MEK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotyp
- IgG
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Applikationshinweise
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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Andere Bezeichnung
- MEK1
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Hintergrund
- Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
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Molekulargewicht
- 45 kDa
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NCBI Accession
- NP_002746
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UniProt
- Q02750
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Pathways
- MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Target
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