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C-JUN Antikörper (pThr91)

JUN Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN361913
  • Target Alle C-JUN (JUN) Antikörper anzeigen
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Bindungsspezifität
    • 45
    • 42
    • 38
    • 28
    • 20
    • 16
    • 16
    • 15
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr91
    Reaktivität
    • 371
    • 194
    • 176
    • 33
    • 26
    • 21
    • 17
    • 17
    • 16
    • 12
    • 11
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 362
    • 17
    • 1
    Kaninchen
    Klonalität
    • 337
    • 43
    Polyklonal
    Konjugat
    • 182
    • 20
    • 12
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 11
    • 11
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Dieser C-JUN Antikörper ist unkonjugiert
    Applikation
    • 245
    • 118
    • 108
    • 94
    • 64
    • 50
    • 42
    • 41
    • 40
    • 23
    • 11
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    The antibody detects endogenous level of c-Jun only when phosphorylated at threonine 91.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pThr91 (T-T-T (p) -P-T) derived from Human c-Jun. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product JUN Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Saha, Jiang, Yang, Zhu, Wang, Schimmer, Qiu, Chang: "Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma." in: PLoS ONE, Vol. 7, Issue 1, pp. e30215, (2012) (PubMed).

  • Target
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Andere Bezeichnung
    c-Jun (JUN Produkte)
    Hintergrund
    Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
    Molekulargewicht
    43 kDa
    NCBI Accession
    NP_002219
    UniProt
    P05412
    Pathways
    MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteine
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