PRKAG3 Antikörper (Middle Region)

Produktnummer ABIN359119

Produktdetails anti-PRKAG3 Antikörper

Target: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKAG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to PRKAG3.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PRKAG3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu PRKAG3

Target: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Andere Bezeichnung: AMPK gamma-3 Chain / AMPKG3 (PRKAG3 Produkte)

Synonyme: Ampkg3 antikoerper, prkag3-a antikoerper, PRKAG3 antikoerper, AMPKG3 antikoerper, AMPKg3L antikoerper, AMPKg3S antikoerper, Amkg3 antikoerper, protein kinase AMP-activated non-catalytic subunit gamma 3 antikoerper, protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b antikoerper, protein kinase, AMP-activated, gamma 3 non-catatlytic subunit antikoerper, Prkag3 antikoerper, PRKAG3 antikoerper, prkag3.S antikoerper, prkag3-b antikoerper

Hintergrund: PRKAG3 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pigcounterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.Synonyms: 5'-AMP-activated protein kinase subunit gamma-3, AMPK gamma 3, PRKAG3

Gen-ID: 53632, 9606

UniProt: Q9UGI9

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effekt