NR4A1 Antikörper (pSer351)

Produktnummer ABIN358306

Produktdetails anti-NR4A1 Antikörper

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Bindungsspezifität: pSer351

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR4A1 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Spezifität: This antibody detects NAK1/NR4A1 pSer351 . Predicted to cross react with Mouse (100 % Antigen Homology).

Aufreinigung: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S351 of human NR4A1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Dot Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu NR4A1

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Andere Bezeichnung: NAK1 (NR4A1 Produkte)

Synonyme: GFRP1 antikoerper, HMR antikoerper, N10 antikoerper, NAK-1 antikoerper, NGFIB antikoerper, NP10 antikoerper, NUR77 antikoerper, TR3 antikoerper, NGFI-B antikoerper, Gfrp antikoerper, Hbr-1 antikoerper, Hbr1 antikoerper, Hmr antikoerper, TIS1 antikoerper, nur77 antikoerper, Ngfi-b antikoerper, Nur77 antikoerper, nuclear receptor subfamily 4 group A member 1 antikoerper, nuclear receptor subfamily 4, group A, member 1 antikoerper, NR4A1 antikoerper, Nr4a1 antikoerper

Hintergrund: NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.Synonyms: Early Response Protein NAK1, GFRP1, HMR, N10, NR4A1, NUR77, Orphan Nuclear Receptor HMR, ST-59, TR3 Orphan Receptor

Molekulargewicht: 64463 Da

Gen-ID: 3164, 9606

UniProt: P22736

Pathways: Fc-epsilon Rezeptor Signalübertragung, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Steroid Hormone Mediated Signaling Pathway