NR4A1 Antikörper (Ser351)

Produktnummer ABIN7180055

Produktdetails anti-NR4A1 Antikörper

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Bindungsspezifität: Ser351

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR4A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human Nuclear Receptor NR4A1 around the phosphorylation site of serine 351 (L-P-S(p)-K-P).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NR4A1

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Andere Bezeichnung: NR4A1 (NR4A1 Produkte)

Synonyme: GFRP1 antikoerper, HMR antikoerper, N10 antikoerper, NAK-1 antikoerper, NGFIB antikoerper, NP10 antikoerper, NUR77 antikoerper, TR3 antikoerper, NGFI-B antikoerper, Gfrp antikoerper, Hbr-1 antikoerper, Hbr1 antikoerper, Hmr antikoerper, TIS1 antikoerper, nur77 antikoerper, Ngfi-b antikoerper, Nur77 antikoerper, nuclear receptor subfamily 4 group A member 1 antikoerper, nuclear receptor subfamily 4, group A, member 1 antikoerper, NR4A1 antikoerper, Nr4a1 antikoerper

Hintergrund:

Background: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' By similarity. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.

Nakai A., Mol. Endocrinol. 4:1438-1443(1990).
Chang C., J. Steroid Biochem. 34:391-395(1989).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: Early response protein NAK1 antibody, GFRP 1 antibody, GFRP antibody, GFRP1 antibody, Growth factor inducible nuclear protein N10 antibody, Growth Factor Inducible Nuclear Protein NP10 antibody, Growth Factor Response Protein 1 antibody, Hbr1 antibody, HMR antibody, Hormone Receptor antibody, MGC9485 antibody, N10 antibody, N10 nuclear protein antibody, NAK 1 antibody, NAK1 antibody, Nerve growth factor IB nuclear receptor variant 1 antibody, NGFIB antibody, NP 10 antibody, NP10 antibody, NR4A1 antibody, NR4A1_HUMAN antibody, Nuclear hormone receptor NUR/77 antibody, Nuclear Hormone Receptor TR3 antibody, Nuclear receptor subfamily 4 group A member 1 antibody, NUR77 antibody, NUR77, mouse, homolog of antibody, Orphan nuclear receptor HMR antibody, Orphan nuclear receptor NR4A1 antibody, Orphan nuclear receptor TR3 antibody, Orphan receptor tr3 antibody, Receptor NGFIB antibody, ST 59 antibody, ST-59 antibody, ST59 antibody, Steroid receptor TR3 antibody, Testicular receptor 3 antibody, TR 3 antibody, TR3 antibody, TR3 orphan receptor antibody

UniProt: P22736

Pathways: Fc-epsilon Rezeptor Signalübertragung, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Steroid Hormone Mediated Signaling Pathway