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E-cadherin Antikörper (N-Term)

Name: E-cadherin Antikörper (N-Term)
SKU: ABIN356994
Price: 869.85 EUR
Availability: InStock

CDH1 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated

Image no. 2 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (N-Term) antibody (ABIN356994) (E-cadherin Antikörper (N-Term))

Image no. 1 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (N-Term) antibody (ABIN356994) (E-cadherin Antikörper (N-Term))

2 Abbildungen

Produktnummer ABIN356994

Datenblatt (PDF)

Target Alle E-cadherin (CDH1) Antikörper anzeigen

E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
Bindungsspezifität
17

17

16

11

10

10

8

8

7

7

5

4

4

4

4

4

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
238

101

87

18

17

16

9

9

9

6

4

4

4

4

1

1

1

1

1

1
Human, Maus
Wirt
190

81

8

7
Kaninchen
Passende Sekundärantikörper
Klonalität
178

107

1
Polyklonal
Konjugat
136

34

28

8

8

8

8

7

7

6

6

6

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser E-cadherin Antikörper ist unkonjugiert
Applikation
194

92

89

63

55

55

36

33

29

27

17

16

5

4

4

4

3

3

3

2

1

1

1

1

1

1

1
Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität

This antibody detects E Cadherin (CDH1) at N-term.

Aufreinigung

Purified

Immunogen

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CDH1.

Isotyp

Ig Fraction

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CDH1 Reaktivität: Human, Maus, Ratte, Schwein, Affe, Hund, Huhn, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Avian, Cat, Esel, Ziege, Hamster, Schaf WB, IHC Wirt: Ziege Polyclonal unconjugated

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Applikationshinweise

ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.25 mg/mL

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Target

E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Andere Bezeichnung

CD324 / Cadherin-1 (CDH1 Produkte)

Synonyme

Arc-1 antikoerper, CD324 antikoerper, CDHE antikoerper, ECAD antikoerper, LCAM antikoerper, UVO antikoerper, E-cadherin antikoerper, cdh1 antikoerper, si:dz180o5.2 antikoerper, uvo antikoerper, lcam antikoerper, E-Cad antikoerper, XBcad antikoerper, l-cam antikoerper, xcdh1 antikoerper, cdhc-A antikoerper, xb-cad antikoerper, XTCAD-1 antikoerper, c-cadherin antikoerper, cadherin-1 antikoerper, uvomorulin antikoerper, XB-cadherin antikoerper, arc-1 antikoerper, cd324 antikoerper, cdhe antikoerper, ecad antikoerper, AA960649 antikoerper, E-cad antikoerper, Ecad antikoerper, L-CAM antikoerper, Um antikoerper, cadherin 1 antikoerper, si:busm1-180o5.2 antikoerper, cadherin 1, type 1, E-cadherin (epithelial) antikoerper, cadherin 1, type 1 S homeolog antikoerper, CDH1 antikoerper, si:busm1-180o5.2 antikoerper, cdh1 antikoerper, Cdh1 antikoerper, cdh1.S antikoerper

Hintergrund

CDH1 is a classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization.Synonyms: CAM 120/80, CDH1, CDHE, E-cadherin, Epithelial cadherin, UVO, Uvomorulin

Molekulargewicht

97456 Da

Gen-ID

999, 9606

UniProt

P12830

Pathways

WNT Signalweg, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation