KCNQ4 Antikörper (N-Term)

Produktnummer ABIN347255

Produktdetails anti-KCNQ4 Antikörper

Target: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNQ4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Reacts with KCNQ4 from human, mouse and rat protein

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from Nter domain of KCNQ4 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1:100 - 1:1000) WB(1:500 - 1:5000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu KCNQ4

Target: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Andere Bezeichnung: Potassium Voltage-Gated Channel Subfamily KQT Member 4, KCNQ4 (KCNQ4 Produkte)

Synonyme: KCNQ4 antikoerper, k(v)7.4 antikoerper, kv7.4 antikoerper, DFNA2 antikoerper, DFNA2A antikoerper, KV7.4 antikoerper, potassium voltage-gated channel subfamily Q member 4 antikoerper, potassium channel, voltage gated KQT-like subfamily Q, member 4 antikoerper, potassium voltage-gated channel, subfamily Q, member 4 antikoerper, KCNQ4 antikoerper, kcnq4 antikoerper, Kcnq4 antikoerper

Hintergrund: Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinnic receptors

UniProt: P56696

Pathways: Sensory Perception of Sound