MAF Antikörper

Produktnummer ABIN346927

Produktdetails anti-MAF Antikörper

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoelectron Microscopy (IEM)

Spezifität: Reacts with human 47 kDa Maf protein derived from a transfected CEFcell line

Aufreinigung: Antiserum

Immunogen: Maf-GST fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC : 1/50 to 1/500 - WB : 1/200 to 1/5 000 Useful for electrophoretic mobility shift assay (EMSA)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu MAF

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Andere Bezeichnung: Transcription Factor Maf (MAF Produkte)

Synonyme: MAF antikoerper, DKFZp459D1731 antikoerper, 2810401A20Rik antikoerper, A230108G15Rik antikoerper, AW047063 antikoerper, c-maf antikoerper, CCA4 antikoerper, c-MAF antikoerper, Maf2 antikoerper, cMaf antikoerper, Z-cmaf antikoerper, c-Maf antikoerper, fl13d12 antikoerper, wu:fl13d12 antikoerper, C-Maf antikoerper, MAF bZIP transcription factor antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) antikoerper, avian musculoaponeurotic fibrosarcoma oncogene homolog antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a) antikoerper, MAF antikoerper, Maf antikoerper, mafa antikoerper

Hintergrund: Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

NCBI Accession: NP_001026974

UniProt: O75444