TUBGCP5 Antikörper

Produktnummer ABIN317909

Produktdetails anti-TUBGCP5 Antikörper

Target: TUBGCP5 (Tubulin, gamma Complex Associated Protein 5 (TUBGCP5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBGCP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: GCP5 antibody detects endogenous levels of GCP5 protein.(region surrounding Ile779)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TUBGCP5

Target: TUBGCP5 (Tubulin, gamma Complex Associated Protein 5 (TUBGCP5))

Andere Bezeichnung: TUBGCP5 (TUBGCP5 Produkte)

Synonyme: wu:fa03b04 antikoerper, wu:fe01d03 antikoerper, zgc:110217 antikoerper, GCP5 antikoerper, B130010C12Rik antikoerper, mKIAA1899 antikoerper, tubulin gamma complex associated protein 5 antikoerper, tubulin, gamma complex associated protein 5 antikoerper, TUBGCP5 antikoerper, tubgcp5 antikoerper, Tubgcp5 antikoerper

Hintergrund: The γ-Tubulin complex is composed of γ Tubulin and the γ-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. γ-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the γ-Tubulin complex. GCP5 (γ-Tubulin complex component 5), also known as TUBGCP5, is a 1,024 amino acid member of the γ-Tubulin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior and lower intellectual ability.Synonyms: GCP-5, GCP5, Gamma-tubulin complex component 5, KIAA1899

Molekulargewicht: approx. 118 kDa

Gen-ID: 114791

NCBI Accession: NP_001096080

UniProt: Q96RT8

Pathways: M Phase