TRHR Antikörper

Produktnummer ABIN317876

Produktdetails anti-TRHR Antikörper

Target: TRHR (Thyrotropin-Releasing Hormone Receptor (TRHR))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRHR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TRHR

Target: TRHR (Thyrotropin-Releasing Hormone Receptor (TRHR))

Andere Bezeichnung: TRHR (TRHR Produkte)

Synonyme: TRH-R1 antikoerper, TRH-R antikoerper, GPCR antikoerper, trhr-A antikoerper, xtrhr antikoerper, TRH-RECEPTOR antikoerper, thyrotropin-releasing hormone receptor antikoerper, thyrotropin releasing hormone receptor antikoerper, thyrotropin releasing hormone receptor S homeolog antikoerper, Tsp_09695 antikoerper, Trhr antikoerper, TRHR antikoerper, trhr.S antikoerper

Hintergrund: Thyrotrophin-releasing hormone (TRH) is a hypothalamic tripeptide that stimulates, via its receptor in the anterior pituitary gland, the release of thyrotrophin (TSH) and prolactin. The TRH receptors, TRH-R1 and TRH-R2, are G protein-coupled proteins containing seven transmembrane domains and other conserved regions. In rat, two isoforms exist, TRH-R (412) and TRH-R (387), that differ at their carboxy termini. TRH receptors are distributed throughout the central and peripheral nervous systems and are present in a variety of tissues. TRH-R2 displays 50 % homology to TRH-R1 and is more restricted to the central nervous system than TRH-R1. Mutation in the TRH receptor gene is associated with isolated central hypothyroidism, a rare disorder characterized by insufficient TSH secretion resulting in low levels of thyroid hormones.Synonyms: TRH-R, Thyroliberin receptor 1, Thyrotropin-releasing hormone receptor

Molekulargewicht: approx. 50 kDa