PTGDR Antikörper

Produktnummer ABIN317875

Produktdetails anti-PTGDR Antikörper

Target: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGDR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Spezifität: PD2R antibody detects endogenous levels of PD2R protein.(region surrounding Glu301)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PTGDR

Target: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Andere Bezeichnung: PTGDR (PTGDR Produkte)

Synonyme: AS1 antikoerper, ASRT1 antikoerper, DP antikoerper, DP1 antikoerper, PTGDR1 antikoerper, Ptgdr antikoerper, Ptgdr2 antikoerper, PTGDR antikoerper, PGD antikoerper, prostaglandin D2 receptor antikoerper, prostaglandin D receptor antikoerper, PTGDR antikoerper, Ptgdrl antikoerper, Ptgdr antikoerper

Hintergrund: The prostaglandin D2 receptor is a member of the G-protein-coupled receptor (GPCR) family (subfamily: prostanoid). It has been shown to function as a prostanoid DP receptor. Its activity is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. Prostaglandin D2 receptor has been reported to be expressed in human small intestine, colon (goblet cells), eye, and eosinophils. ESTs have been isolated from human brain libraries.Synonyms: ASRT1, PGD receptor, PGD2 receptor, Prostaglandin D2 receptor, Prostanoid DP receptor

Molekulargewicht: approx. 40 kDa

Gen-ID: 5729

NCBI Accession: NP_000944

UniProt: Q13258

Pathways: Thromboxane A2 Receptor Signaling