PTGDR Antikörper

Produktnummer ABIN7075206

Produktdetails anti-PTGDR Antikörper

Target: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGDR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Prostaglandin D2 Receptor

Anwendungsinformationen

Applikationshinweise: WB (M,R) 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu PTGDR

Target: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Andere Bezeichnung: Prostaglandin D2 Receptor (PTGDR Produkte)

Synonyme: AS1 antikoerper, ASRT1 antikoerper, DP antikoerper, DP1 antikoerper, PTGDR1 antikoerper, Ptgdr antikoerper, Ptgdr2 antikoerper, PTGDR antikoerper, PGD antikoerper, prostaglandin D2 receptor antikoerper, prostaglandin D receptor antikoerper, PTGDR antikoerper, Ptgdrl antikoerper, Ptgdr antikoerper

Hintergrund: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate . Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR.

Molekulargewicht: 50 kDa

Gen-ID: 19214

NCBI Accession: NP_032988

UniProt: P70263

Pathways: Thromboxane A2 Receptor Signaling