PTGDR Antikörper
Kurzübersicht für PTGDR Antikörper (ABIN7075206)
Target
Alle PTGDR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse Prostaglandin D2 Receptor
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Applikationshinweise
- WB (M,R) 1:1000-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- PTGDR (Prostaglandin D2 Receptor (PTGDR))
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Andere Bezeichnung
- Prostaglandin D2 Receptor
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Hintergrund
- Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate . Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR.
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Molekulargewicht
- 50 kDa
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Gen-ID
- 19214
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NCBI Accession
- NP_032988
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UniProt
- P70263
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Pathways
- Thromboxane A2 Receptor Signaling
Target
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