LTBR Antikörper (Extracellular Domain) (PE)

Produktnummer ABIN317402

Produktdetails anti-LTBR Antikörper (PE)

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Bindungsspezifität: Extracellular Domain

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser LTBR Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody recognises lymphotoxin-beta receptor (LT beta R), a member of the tumour necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognises surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (2). This product is routinely tested on mouse WEHI cells.

Produktmerkmale: Synonyms: Tumor necrosis factor receptor 3, TNF-R3, Tumor necrosis factor C receptor, TNFCR,TNFRSF3, D12S370, Lymphotoxin-beta receptor, Tumor necrosis factor receptor superfamilymember 3, Tumor necrosis factor receptor type III, Tumor necrosis factor receptor 2-relatedprotein

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Recombinant extracellular domain of LT beta R

Klon: 5G11b

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Reconstitute with 1.0 mL distilled water

Konzentration: 0.05 mg/mL

Buffer: Phosphate buffered saline pH 7.4, 0.09 % Sodium Azide, 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody prior and following reconstitution at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu LTBR

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Andere Bezeichnung: LTBR / TNFR3 (LTBR Produkte)

Synonyme: AI256028 antikoerper, CD18 antikoerper, LTbetaR antikoerper, Ltar antikoerper, TNF-R-III antikoerper, TNFCR antikoerper, TNFR-RP antikoerper, TNFR2-RP antikoerper, TNFRrp antikoerper, Tnfbr antikoerper, Tnfrsf3 antikoerper, D12S370 antikoerper, LT-BETA-R antikoerper, TNFR3 antikoerper, TNFRSF3 antikoerper, lymphotoxin beta receptor antikoerper, lymphotoxin B receptor antikoerper, Ltbr antikoerper, LTBR antikoerper

Hintergrund: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin alpha and lymphtoxin beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.Synonyms: D12S370, Lymphotoxin-beta receptor, TNF-R3, TNFCR, TNFRSF3, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor 3, Tumor necrosis factor receptor superfamily member 3, Tumor necrosis factor receptor type III

Gen-ID: 4055

UniProt: P36941

Pathways: NF-kappaB Signalweg