IL-4 Antikörper

Produktnummer ABIN317377

Produktdetails anti-IL-4 Antikörper

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reaktivität: Hund, Rind (Kuh), Schwein, Schaf, Marder, Ziege

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-4 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Spezifität: This antibody recognises bovine interleukin 4.

Produktmerkmale: Synonyms: IL-4, BSF1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra, B-cell stimulatory factor1

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Klon: CC303

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA. Flow Cytometry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containssodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled bytrained staff only.

Haltbarkeit: 12 months

Details zu IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Andere Bezeichnung: Interleukin-4 / IL4 (IL4 Produkte)

Synonyme: IL4 antikoerper, IL-4 antikoerper, BCGF-1 antikoerper, BCGF1 antikoerper, BSF-1 antikoerper, BSF1 antikoerper, Il-4 antikoerper, Il4e12 antikoerper, IL2 antikoerper, interleukin 4 antikoerper, IL4 antikoerper, Il4 antikoerper

Hintergrund: IL4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.Synonyms: B-cell stimulatory factor 1, BSF1, Binetrakin, IL-4, Lymphocyte stimulatory factor 1, Pitrakinra

Gen-ID: 3565

UniProt: P05112

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation