PPAP2A Antikörper

Produktnummer ABIN306892

Produktdetails anti-PPAP2A Antikörper

Target: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPAP2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Produktmerkmale: EC 3.1.3.4, Lipid Phosphate Phosphatase 1, Phosphatidic acid phosphatase 2a,Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. It catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG), and is a pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. It is a major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. It may control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. Its down-regulation may contribute to the development of colon adenocarcinoma.

Immunogen: Synthetic peptide derived from the LPP1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu PPAP2A

Target: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Andere Bezeichnung: Lysophospholipid Phosphatase (LPP) 1/1A (PPAP2A Produkte)

Synonyme: PPAP2A antikoerper, wun antikoerper, LLP1a antikoerper, LPP1 antikoerper, PAP-2a antikoerper, PAP2 antikoerper, Hic53 antikoerper, Hpic53 antikoerper, LPP-1 antikoerper, mPAP antikoerper, PAP2A antikoerper, PAP2a2 antikoerper, phospholipid phosphatase 1 antikoerper, phosphatidic acid phosphatase type 2A antikoerper, phospholipid phosphatase 1 L homeolog antikoerper, PLPP1 antikoerper, plpp1 antikoerper, Ppap2a antikoerper, plpp1.L antikoerper, Plpp1 antikoerper

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway