PPAP2A Antikörper (C-Term)

Produktnummer ABIN6242907

Produktdetails anti-PPAP2A Antikörper

Target: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Bindungsspezifität: AA 270-304, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPAP2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPAP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 270-304 amino acids from the C-terminal region of human PPAP2A.

Klon: RB51855

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu PPAP2A

Target: PPAP2A (Phosphatidic Acid Phosphatase Type 2A (PPAP2A))

Andere Bezeichnung: PPAP2A (PPAP2A Produkte)

Synonyme: PPAP2A antikoerper, wun antikoerper, LLP1a antikoerper, LPP1 antikoerper, PAP-2a antikoerper, PAP2 antikoerper, Hic53 antikoerper, Hpic53 antikoerper, LPP-1 antikoerper, mPAP antikoerper, PAP2A antikoerper, PAP2a2 antikoerper, phospholipid phosphatase 1 antikoerper, phosphatidic acid phosphatase type 2A antikoerper, phospholipid phosphatase 1 L homeolog antikoerper, PLPP1 antikoerper, plpp1 antikoerper, Ppap2a antikoerper, plpp1.L antikoerper, Plpp1 antikoerper

Hintergrund: Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma.

Molekulargewicht: 32156

UniProt: O14494

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway