PTGER2 Antikörper

Produktnummer ABIN306864

Produktdetails anti-PTGER2 Antikörper

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTGER2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Rind (Kuh), Human, Ratte

Produktmerkmale: Prostaglandin E2 Receptor Subtype EP2, Provided under license from Allergan, Inc. United States Patent No. 5,716,835,Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.

Aufreinigung: Protein A/G Chromatography

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human EP2 receptor protein and mouse myeloma cells.

Klon: 3E6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: This antibody can be used for Western blot analysis (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu PTGER2

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Andere Bezeichnung: Prostaglandin-E2 receptor EP2 (PTGER2 Produkte)

Synonyme: EP2 antikoerper, Ptgerep2 antikoerper, ptger2 antikoerper, ptger2l antikoerper, zgc:63974 antikoerper, MGC69060 antikoerper, PTGER2 antikoerper, Ptger-ep2 antikoerper, si:ch211-13n20.1 antikoerper, si:dkey-29m11.3 antikoerper, zgc:136608 antikoerper, prostaglandin E receptor 2 antikoerper, prostaglandin E receptor 2 (subtype EP2) antikoerper, prostaglandin E receptor 2a (subtype EP2) antikoerper, prostaglandin E receptor 2 S homeolog antikoerper, prostaglandin E receptor 2b (subtype EP2) antikoerper, PTGER2 antikoerper, Ptger2 antikoerper, ptger2a antikoerper, ptger2.S antikoerper, ptger2b antikoerper

UniProt: Q62928