TRAM2 Antikörper (C-Term)

Produktnummer ABIN3044050

Produktdetails anti-TRAM2 Antikörper

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Bindungsspezifität: AA 309-325, C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Translocating chain-associated membrane protein 2(TRAM2) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: RFIHSQLRHW REYWKEQ

Kreuzreaktivität (Details): Predicted Cross Reactivity: human, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Translocating chain-associated membrane protein 2(TRAM2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: translocation associated membrane protein 2
Protein Name: Translocating chain-associated membrane protein 2

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse TRAM2(309-325aa RFIHSQLRHWREYWKEQ), identical to the related rat sequence, and different from the related human sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Predicted Species: Human, Rat, The detection limit for TRAM2 is approximately 5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TRAM2

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Andere Bezeichnung: TRAM2 (TRAM2 Produkte)

Synonyme: C330003D03Rik antikoerper, wu:fb20c11 antikoerper, wu:fi23a12 antikoerper, zgc:111902 antikoerper, zgc:55869 antikoerper, zgc:76937 antikoerper, tram2 antikoerper, translocation associated membrane protein 2 antikoerper, tram-like protein antikoerper, TraM-like protein antikoerper, translocating chain-associating membrane protein 2 antikoerper, translocation associated membrane protein 2 L homeolog antikoerper, TRAM2 antikoerper, CJE0444 antikoerper, BT_p548215 antikoerper, traM antikoerper, CJJ81176_0418 antikoerper, Tram2 antikoerper, tram2 antikoerper, tram2.L antikoerper

Hintergrund: TRAM2(Translocation-Associating Membrane Protein 2), also called KIAA0057, is a protein that in humans is encoded by the TRAM2 gene. TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum(ER) membrane. By genomic sequence analysis, Onuchic et al.(1999) mapped the TRAM2 gene to chromosome 6p21.1-p12 near the PKHD1 gene. Upon activation, quiescent hepatic stellate cells proliferate, change morphologically into myofibroblasts, and increase their synthesis of extracellular matrix proteins. Stefanovic et al.(2004) demonstrated that both TRAM2 and collagen type I are upregulated in activated rat and human hepatic stellate cells.

Synonyms: C330003D03Rik antibody|KIAA0057 antibody|MGC25725 antibody|OTTHUMP00000016607 antibody|TRAM like protein antibody|Tram2 antibody|TRAM2_HUMAN antibody|Translocating chain associating membrane protein 2 antibody|Translocating chain-associated membrane protein 2 antibody|Translocation associated membrane protein 2 antibody

UniProt: Q924Z5