TRAM2 Antikörper (C-Term)

Produktnummer ABIN6265712

Produktdetails anti-TRAM2 Antikörper

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: TRAM2 Antibody detects endogenous levels of total TRAM2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TRAM2, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TRAM2

Target: TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))

Andere Bezeichnung: TRAM2 (TRAM2 Produkte)

Synonyme: C330003D03Rik antikoerper, wu:fb20c11 antikoerper, wu:fi23a12 antikoerper, zgc:111902 antikoerper, zgc:55869 antikoerper, zgc:76937 antikoerper, tram2 antikoerper, translocation associated membrane protein 2 antikoerper, tram-like protein antikoerper, TraM-like protein antikoerper, translocating chain-associating membrane protein 2 antikoerper, translocation associated membrane protein 2 L homeolog antikoerper, TRAM2 antikoerper, CJE0444 antikoerper, BT_p548215 antikoerper, traM antikoerper, CJJ81176_0418 antikoerper, Tram2 antikoerper, tram2 antikoerper, tram2.L antikoerper

Hintergrund:

Description: Necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) (PubMed:27499293).

Gene: TRAM2

Molekulargewicht: 43 kDa

Gen-ID: 9697

UniProt: Q15035