SLC6A4 Antikörper (N-Term)

Produktnummer ABIN3043931

Produktdetails anti-SLC6A4 Antikörper

Target: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Bindungsspezifität: AA 57-85, N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC6A4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB, IHC-P in Human,Rat.

Sequenz: DDTRHSIPAT TTTLVAELHQ GERETWGKK

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Protein Name: Sodium-dependent serotonin transporter

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SLC6A4 (57-85aa DDTRHSIPATTTTLVAELHQGERETWGKK), different from the related mouse and rat sequences by six amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SLC6A4 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu SLC6A4

Target: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Andere Bezeichnung: SLC6A4 (SLC6A4 Produkte)

Synonyme: 5-HTT antikoerper, 5-HTTLPR antikoerper, 5HTT antikoerper, HTT antikoerper, OCD1 antikoerper, SERT antikoerper, SERT1 antikoerper, hSERT antikoerper, AI323329 antikoerper, Htt antikoerper, Sert antikoerper, CG4545 antikoerper, DmSERT antikoerper, DmSerT antikoerper, Dmel\\CG4545 antikoerper, dSERT antikoerper, dSERT1 antikoerper, dSerT antikoerper, dSert antikoerper, dsert antikoerper, SLC6A4 antikoerper, solute carrier family 6 member 4 antikoerper, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antikoerper, Serotonin transporter antikoerper, huntingtin antikoerper, solute carrier family 6 (neurotransmitter transporter), member 4b antikoerper, solute carrier family 6 (neurotransmitter transporter), member 4a antikoerper, SLC6A4 antikoerper, Slc6a4 antikoerper, SerT antikoerper, LOC100540532 antikoerper, slc6a4 antikoerper, slc6a4b antikoerper, slc6a4a antikoerper

Hintergrund: SLC6A4 (Solute carrier family 6, member 4), also known as SERT (serotonin transporter), is a monoamine transporter protein. The SLC6A4 gene spans 31 kb and contains 14 exons. This protein integral membrane protein transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium: neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma.

Synonyms: 5 HTT antibody|5 HTTLPR antibody|5 hydroxytryptamine (serotonin) transporter antibody|5 hydroxytryptamine transporter antibody|5HT transporter antibody|5HTT antibody|hSERT antibody|HTT antibody|Na+/Cl- dependent serotonin transporter antibody|OCD1 antibody| SC6A4_HUMAN antibody|Serotonin transporter 1 antibody|SERT antibody|SERT1 antibody|SLC6A4 antibody|Sodium dependent serotonin transporter antibody|Sodium-dependent serotonin transporter antibody|Solute carrier family 6 (neurotransmitter transporter) member 4 antibody|solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antibody|Solute carrier family 6 member 4 antibody

Gen-ID: 6532

UniProt: P31645