SLC6A4 Antikörper (AA 401-500)

Produktnummer ABIN735983

Produktdetails anti-SLC6A4 Antikörper

Target: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Bindungsspezifität: AA 401-500

Reaktivität: Human, Ratte, Maus, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC6A4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5-HTT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SLC6A4 Antikörper (ABIN735983)

Yu, Huang, Zhang, Ye, Chi, Zou, Lv, Zheng: "Comparison of 5-hydroxytryptophan signaling pathway characteristics in diarrhea-predominant irritable bowel syndrome and ulcerative colitis." in: World journal of gastroenterology, Vol. 22, Issue 12, pp. 3451-9, (2016) (PubMed).

Wang, Gu, Liu, Bai, Wang: "Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats." in: Molecular medicine reports, Vol. 15, Issue 2, pp. 673-680, (2016) (PubMed).

Wojtal, Cee, Lang, Götze, Frühauf, Geier, Pastor-Anglada, Torres-Torronteras, Martí, Fried, Lutz, Maggiorini, Gassmann, Rogler, Vavricka: "Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 307, Issue 7, pp. G673-88, (2014) (PubMed).

Wang, Liu, Wang, Bai, Zhang, Sun, Wang: "Involvement of serotonin mechanism in methamphetamine-induced chronic pulmonary toxicity in rats." in: Human & experimental toxicology, (2013) (PubMed).

Dong, Li, Zheng, Mu, Zhang, Liu: "A representative prescription for emotional disease, Ding-Zhi-Xiao-Wan restores 5-HT system deficit through interfering the synthesis and transshipment in chronic mild stress-induced depressive rats." in: Journal of ethnopharmacology, Vol. 150, Issue 3, pp. 1053-61, (2013) (PubMed).

Bai, Wang, Liu, Wang, Lian, Zhang, Kang, Wang: "4-Chloro-DL-phenylalanine protects against monocrotaline‑induced pulmonary vascular remodeling and lung inflammation." in: International journal of molecular medicine, Vol. 33, Issue 2, pp. 373-82, (2013) (PubMed).

Details zu SLC6A4

Target: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Andere Bezeichnung: SLC6A4/5-HTT (SLC6A4 Produkte)

Synonyme: 5-HTT antikoerper, 5-HTTLPR antikoerper, 5HTT antikoerper, HTT antikoerper, OCD1 antikoerper, SERT antikoerper, SERT1 antikoerper, hSERT antikoerper, AI323329 antikoerper, Htt antikoerper, Sert antikoerper, CG4545 antikoerper, DmSERT antikoerper, DmSerT antikoerper, Dmel\\CG4545 antikoerper, dSERT antikoerper, dSERT1 antikoerper, dSerT antikoerper, dSert antikoerper, dsert antikoerper, SLC6A4 antikoerper, solute carrier family 6 member 4 antikoerper, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 antikoerper, Serotonin transporter antikoerper, huntingtin antikoerper, solute carrier family 6 (neurotransmitter transporter), member 4b antikoerper, solute carrier family 6 (neurotransmitter transporter), member 4a antikoerper, SLC6A4 antikoerper, Slc6a4 antikoerper, SerT antikoerper, LOC100540532 antikoerper, slc6a4 antikoerper, slc6a4b antikoerper, slc6a4a antikoerper

Hintergrund:

Synonyms: HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR, Sodium-dependent serotonin transporter, 5HT transporter, Solute carrier family 6 member 4, SLC6A4

Background: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.

Gen-ID: 6532

UniProt: P31645