ABCG5 Antikörper (N-Term)
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- Target Alle ABCG5 Antikörper anzeigen
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
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Bindungsspezifität
- AA 197-221, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABCG5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 5(ABCG5) detection. Tested with WB in Human.
- Sequenz
- ERRRVSIAAQ LLQDPKVMLF DEPTT
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 5(ABCG5) detection. Tested with WB in Human.
Gene Name: ATP-binding cassette, sub-family G (WHITE), member 5
Protein Name: ATP-binding cassette sub-family G member 5 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human ABCG5 (197-221aa ERRRVSIAAQLLQDPKVMLFDEPTT), different from the related mouse and rat sequences by two amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ABCG5 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human , The detection limit for ABCG5 is approximately 0.1 ng/lane under reducing conditions.
Notes: WB: The detection limit for ABCG5 is approximately 0.1 ng/lane under reducing conditions. Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
- Andere Bezeichnung
- ABCG5 (ABCG5 Produkte)
- Synonyme
- DDBDRAFT_0205617 antikoerper, DDBDRAFT_0215344 antikoerper, DDB_0205617 antikoerper, DDB_0215344 antikoerper, STSL antikoerper, AW112016 antikoerper, cmp antikoerper, sterolin-1 antikoerper, trac antikoerper, ATP binding cassette subfamily G member 5 antikoerper, ATP-binding cassette, sub-family G (WHITE), member 5 antikoerper, ABC transporter G family protein antikoerper, ABCG5 antikoerper, abcg5 antikoerper, abcG5 antikoerper, Abcg5 antikoerper
- Hintergrund
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ABCG5 (Atp-binding cassette, subfamily g, member 5) also known as STEROLIN 1, is a protein that in humans is encoded by the ABCG5 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. The ABCG5 gene contains 13 exons and spans about 28 kb. The ABCG5 gene is mapped on 2p21. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. Small (2003) reviewed the role of ABC transporters in secretion of cholesterol from liver into bile, particularly the role of ABCG5/ABCG8. The ABCG5 and ABCG8 genes are an example of closely neighboring genes in a head-to-head orientation that, when mutated, cause the same phenotype.
Synonyms: ABCG5 antibody|ABCG5_HUMAN antibody|ATP binding cassette sub family G (WHITE) member 5 (sterolin 1) antibody|ATP binding cassette sub family G member 5 antibody|ATP-binding cassette sub-family G member 5 antibody|Sterolin 1 antibody|Sterolin-1 antibody|STSL antibody - Gen-ID
- 64240
- UniProt
- Q9H222
- Pathways
- Lipid Metabolism
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