SERPINA4 Antikörper (C-Term)

Produktnummer ABIN3043135

Produktdetails anti-SERPINA4 Antikörper

Target: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Bindungsspezifität: AA 384-401, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Kallistatin(SERPINA4) detection. Tested with WB, IHC-P in Human.

Sequenz: AIKFFSAQTN RHILRFNR

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Kallistatin(SERPINA4) detection. Tested with WB, IHC-P in Human.
Gene Name: serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 4
Protein Name: Kallistatin

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kallistatin(384-401aa AIKFFSAQTNRHILRFNR).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SERPINA4

Target: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Andere Bezeichnung: SERPINA4 (SERPINA4 Produkte)

Synonyme: KLKR antikoerper, Klk6 antikoerper, hK1 antikoerper, KAL antikoerper, KLST antikoerper, KST antikoerper, PI-4 antikoerper, PI4 antikoerper, kallistatin antikoerper, SERPINA4 antikoerper, DKFZp469E1737 antikoerper, KALps antikoerper, Klst antikoerper, kallikrein 1 antikoerper, serpin family A member 4 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 antikoerper, serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 antikoerper, KLK1 antikoerper, SERPINA4 antikoerper, Serpina4 antikoerper, SPIA4 antikoerper, Serpina4-ps1 antikoerper

Hintergrund: Serpina 4, also called Kallistatin, PI4 or TISSUE KALLIKREIN INHIBITOR, is a protein that in humans is encoded by the SERPINA4 gene. The serpina4 is a member of the serpin superfamily and represents a major inhibitor of human tissue kallikrein in the circulation. The SERPINA4 gene is localized to 14q32.13. The translated amino acid sequence of serpina4 matches the protein sequence and shares 44 to 46 % sequence identity with other serpin family members. Kallistatin is a serine proteinase inhibitor(serpin) and a heparin-binding protein. It is localized in vascular smooth muscle cells and endothelial cells of blood vessels, suggesting that it may be involved in the regulation of vascular function. And serpina4 also plays a role in neointima hyperplasia.

Synonyms: KAIN_HUMAN antibody|KAL antibody|Kallikrein binding protein antibody|Kallikrein inhibitor antibody|Kallistatin antibody|KBP antibody|KLST antibody|KST antibody|MGC108582 antibody|Peptidase inhibitor 4 antibody|PI-4 antibody|PI4 antibody|Protease inhibitor 4(kallistatin) antibody|Protease inhibitor 4 antibody|Serine(or cysteine) proteinase inhibitor, clade A(alpha 1 antiproteinase, antitrypsin), member 4 antibody|Serpin A4 antibody|Serpin peptidase inhibitor clade A member 4 antibody|Serpin peptidase inhibitor, clade A(alpha 1 antiproteinase, antitrypsin), member 4 antibody|SERPINA4 antibody

UniProt: P29622