Glutamate Receptor 3 Antikörper (Middle Region)

Produktnummer ABIN3042581

Produktdetails anti-Glutamate Receptor 3 Antikörper

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Bindungsspezifität: AA 394-412, Middle Region

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Glutamate receptor 3(GRIA3) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: RKAGYWNEYE RFVPFSDQQ

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Glutamate receptor 3(GRIA3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: glutamate receptor, ionotropic, AMPA 3
Protein Name: Glutamate receptor 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human GRIA3 (394-412aa RKAGYWNEYERFVPFSDQQ), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Andere Bezeichnung: GRIA3 (GRIA3 Produkte)

Synonyme: AMPA antikoerper, gria3 antikoerper, GRIN3A antikoerper, glur3b antikoerper, gria3.2 antikoerper, zfGRIA3[b] antikoerper, si:bz1o18.1 antikoerper, SI:zC231H1.1 antikoerper, si:zc140k5.3 antikoerper, GLUR3 antikoerper, GLUR-C antikoerper, GLUR3/C antikoerper, GRIA3 antikoerper, glur3 antikoerper, GluA3 antikoerper, GluR-3 antikoerper, GluR-C antikoerper, GluR-K3 antikoerper, GLUR-K3 antikoerper, GLURC antikoerper, MRX94 antikoerper, 2900064I19Rik antikoerper, Glur-3 antikoerper, Glur3 antikoerper, Gluralpha3 antikoerper, glutamate receptor, ionotropic, AMPA 3b antikoerper, glutamate ionotropic receptor AMPA type subunit 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 L homeolog antikoerper, glutamate receptor, ionotropic, AMPA3 (alpha 3) antikoerper, gria3b antikoerper, GRIA3 antikoerper, gria3 antikoerper, gria3.L antikoerper, Gria3 antikoerper

Hintergrund: Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. In addition to that, GRIA3 has been shown to interact with GRIP1 and PICK1.

Synonyms: AMPA 3 antibody|AMPA selective glutamate receptor 3 antibody|AMPA-selective glutamate receptor 3 antibody|GluA3 antibody|GLUK3 antibody|GLUR 3 antibody|GLUR C antibody|GLUR K3 antibody|GluR-3 antibody|GluR-C antibody|GluR-K3 antibody|GLUR3 antibody|GLURC antibody|Glutamate receptor 3 antibody|Glutamate receptor C antibody|Glutamate Receptor Ionotrophic AMPA 3 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor subunit 3 antibody|GRIA 3 antibody|Gria3 antibody|GRIA3_HUMAN antibody|GRM 3 antibody|Ionotrophic Glutamate Receptor antibody|Metabotropic glutamate receptor 3 precursor antibody|mGlu 3 antibody|MGLUR 3 antibody|MRX94 antibody

UniProt: P42263

Pathways: PI3K-Akt Signalweg, cAMP Metabolic Process, Synaptic Membrane