LRP5 Antikörper (C-Term)

Produktnummer ABIN3042561

Produktdetails anti-LRP5 Antikörper

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Bindungsspezifität: AA 1201-1215, C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Low-density lipoprotein receptor-related protein 5(LRP5) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: IHAVEEVSLE EFSAH

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Low-density lipoprotein receptor-related protein 5(LRP5) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: low density lipoprotein receptor-related protein 5
Protein Name: Low-density lipoprotein receptor-related protein 5

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LRP5(1201-1215aa IHAVEEVSLEEFSAH), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu LRP5

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Andere Bezeichnung: LRP5 (LRP5 Produkte)

Synonyme: Xlrp5 antikoerper, bmnd1 antikoerper, evr1 antikoerper, evr4 antikoerper, hbm antikoerper, lr3 antikoerper, lrp5-A antikoerper, lrp7 antikoerper, oppg antikoerper, ops antikoerper, opta1 antikoerper, vbch2 antikoerper, LRP5 antikoerper, LRP6 antikoerper, BMND1 antikoerper, EVR1 antikoerper, EVR4 antikoerper, HBM antikoerper, LR3 antikoerper, LRP7 antikoerper, OPPG antikoerper, OPS antikoerper, OPTA1 antikoerper, VBCH2 antikoerper, mKIAA4142 antikoerper, low-density lipoprotein receptor-related protein 5 antikoerper, LDL receptor related protein 5 antikoerper, LDL receptor related protein 5 L homeolog antikoerper, low density lipoprotein receptor-related protein 5 antikoerper, LDL receptor related protein 5 like antikoerper, LOC100147353 antikoerper, LRP5 antikoerper, lrp5.L antikoerper, lrp5 antikoerper, Lrp5 antikoerper, LRP5L antikoerper

Hintergrund: Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the LRP5 gene. It is mapped to 11q13.2. LRP5 is a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with diabetes mellitus type 1 in humans. This protein plays a key role in skeletal homeostasis. In addition to that, the binding of axin to LRP5 is an important part of the Wnt signal transduction pathway, and it also acts as a target for the inhibitory effects of Dickkopf, another developmental protein, on Wnt signaling.

Synonyms: BMND1 antibody|EVR1 antibody|EVR4 antibody|HBM antibody||HGNC:6697 antibody|Low density lipoprotein receptor related protein 5 antibody|Low density lipoprotein receptor related protein 7 antibody|Low-density lipoprotein receptor-related protein 5 antibody|LR3 antibody|LRP-5 antibody|Lrp5 antibody|LRP7 antibody|OPPG antibody|OPS antibody|OPTA1 antibody|Osteoporosis pseudoglioma syndrome antibody|VBCH2 antibody

UniProt: O75197

Pathways: WNT Signalweg, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation