HMOX1 Antikörper (AA 1-288)

Produktnummer ABIN3042449

Produktdetails anti-HMOX1 Antikörper

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Bindungsspezifität: AA 1-288

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Heme oxygenase 1(HMOX1) detection. Tested with WB, IHC-P in Human,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Heme oxygenase 1(HMOX1) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: heme oxygenase (decycling) 1
Protein Name: Heme oxygenase 1

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HMOX1 recombinant protein (Position: M1-M288). Human HMOX1 shares 82% and 80% amino acid (aa) sequences identity with mouse and rat HMOX1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for HMOX1 is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-HMOX1 Antikörper (ABIN3042449)

Wei, Kong, Li, Guan, Wang, Miao: "Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 717, (2018) (PubMed).

Zhu, Chen, Chen, Yang, Xie: "Astaxanthin Promotes Nrf2/ARE Signaling to Alleviate Renal Fibronectin and Collagen IV Accumulation in Diabetic Rats." in: Journal of diabetes research, Vol. 2018, pp. 6730315, (2018) (PubMed).

Wu, Li, Cui, Wu, Hong, Li, Wu, Jie, Wang, Li: "The Natural Flavone Acacetin Confers Cardiomyocyte Protection Against Hypoxia/Reoxygenation Injury via AMPK-Mediated Activation of Nrf2 Signaling Pathway." in: Frontiers in pharmacology, Vol. 9, pp. 497, (2018) (PubMed).

Li Volti, Avola, Tibullo: "Commentary: The apolipoprotein A-I mimetic peptide, D-4F, restrains neointimal formation through heme oxygenase-1 up-regulation." in: Frontiers in pharmacology, Vol. 8, pp. 708, (2017) (PubMed).

Wang, Li, Chen, Jiang, Lu, Zhao: "Hydrogen sulfide accelerates wound healing in diabetic rats." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 5097-104, (2016) (PubMed).

Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).

Guo, Li, Duan, Wang, Zhou, Sun: "Octreotide attenuates liver fibrosis by inhibiting hepatic heme oxygenase-1 expression." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 83-90, (2015) (PubMed).

Guo, Duan, Wang, Zhou, Li, Sun: "Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis." in: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2039-2046, (2015) (PubMed).

Qin, Luo, Gu, Yang, Shen, Gu, Zhang, Gao: "Evidence for a therapeutic effect of Braintone on ischemic brain damage." in: Neural regeneration research, Vol. 8, Issue 19, pp. 1743-55, (2014) (PubMed).

Chen, Wei, He, Yu, Mang, Xu: "Changes of hypoxia-inducible factor-1 signaling and the effect of cilostazol in chronic cerebral ischemia." in: Neural regeneration research, Vol. 8, Issue 19, pp. 1803-13, (2014) (PubMed).

Liu, Wang, Qian, Li: "Xuebijing exerts protective effects on lung permeability leakage and lung injury by upregulating Toll-interacting protein expression in rats with sepsis." in: International journal of molecular medicine, Vol. 34, Issue 6, pp. 1492-504, (2014) (PubMed).

Li, Han, Li, Jiang, Wang: "Upregulation of heat shock protein 32 in Sertoli cells alleviates the impairments caused by heat shock-induced apoptosis in mouse testis." in: Cell stress & chaperones, Vol. 18, Issue 3, pp. 333-51, (2013) (PubMed).

Wang, Li, Lu, Zhao, Xu: "Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats." in: Croatian medical journal, Vol. 54, Issue 2, pp. 171-9, (2013) (PubMed).

Wang, Li, Lu, Zhao: "Riboflavin alleviates cardiac failure in Type I diabetic cardiomyopathy." in: Heart international, Vol. 6, Issue 2, pp. e21, (2012) (PubMed).

Guo, Duan, Li, Sun: "Effect of heme oxygenase-1 on renal function in rats with liver cirrhosis." in: World journal of gastroenterology, Vol. 17, Issue 3, pp. 322-8, (2011) (PubMed).

Xia, Liu, Zhou, Tang, Zou: "Comparison of the effects of propofol and midazolam on inflammation and oxidase stress in children with congenital heart disease undergoing cardiac surgery." in: Yonsei medical journal, Vol. 52, Issue 2, pp. 326-32, (2011) (PubMed).

Wang, Duan, Sun: "Influence of heme oxygenase-1 expression on immune liver fibrosis induced by cobalt protoporphyrin in rats." in: World journal of gastroenterology, Vol. 15, Issue 24, pp. 3009-14, (2009) (PubMed).

Xue, Guo, Li, Hao: "Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats." in: World journal of gastroenterology, Vol. 13, Issue 40, pp. 5384-90, (2007) (PubMed).

Details zu HMOX1

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Andere Bezeichnung: HMOX1 (HMOX1 Produkte)

Synonyme: HMOX1 antikoerper, ARABIDOPSIS THALIANA HEME OXYGENASE 1 antikoerper, ATHO1 antikoerper, F18A8.4 antikoerper, F18A8_4 antikoerper, GENOMES UNCOUPLED 2 antikoerper, GUN2 antikoerper, HEME OXYGENASE antikoerper, HEME OXYGENASE 1 antikoerper, HEME OXYGENASE 6 antikoerper, HO1 antikoerper, HY1 antikoerper, HY6 antikoerper, PLASTID HEME OXYGENASE antikoerper, REVERSAL OF THE DET PHENOTYPE 4 antikoerper, HO-1 antikoerper, wu:fc27c04 antikoerper, zgc:65984 antikoerper, D8Wsu38e antikoerper, Hemox antikoerper, Hmox antikoerper, Hsp32 antikoerper, HEOXG antikoerper, Heox antikoerper, Ho-1 antikoerper, Ho1 antikoerper, hsp32 antikoerper, MGC132176 antikoerper, Hmox1 antikoerper, HMOX1D antikoerper, HSP32 antikoerper, bK286B10 antikoerper, heme oxygenase 1 antikoerper, Plant heme oxygenase (decyclizing) family protein antikoerper, Heme oxygenase antikoerper, heme oxygenase antikoerper, heme oxygenase 1, chloroplastic antikoerper, heme oxygenase 1a antikoerper, heme oxygenase 1 L homeolog antikoerper, HMOX1 antikoerper, TED4 antikoerper, ho1 antikoerper, P9301_RS17555 antikoerper, A9601_RS17590 antikoerper, MAE_RS06565 antikoerper, HO1 antikoerper, hmox1a antikoerper, CPE0214 antikoerper, Cyan7425_2962 antikoerper, Hmox1 antikoerper, hmox1.L antikoerper, AM1_C0205 antikoerper, CC1G_11686 antikoerper, CpipJ_CPIJ007246 antikoerper

Hintergrund: HMOX1 (heme oxygenase (decycling) 1), also known as HO-1, is a human gene that encodes for the enzyme heme oxygenase 1. It is an essential enzyme in heme catabolism, it cleaves heme to form biliverdin. HMOX1 belongs to the heme oxygenase family. The HMOX1 gene is located on the long (q) arm of chromosome 22 at position 12.3, from base pair 34,101,636 to base pair 34,114,748. HMOX1, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. HMOX1 activity is induced by its substrate heme and by various nonheme substances.

Synonyms: 32 kD antibody|bK286B10 antibody|D8Wsu38e antibody|heat shock protein 32 kD antibody|heat shock protein 32kD antibody|Heat shock protein antibody|Heme oxygenase (decycling) 1 antibody|Heme oxygenase 1 antibody|Hemox antibody|HMOX 1 antibody|Hmox antibody|HMOX1 antibody|HMOX1_HUMAN antibody|HO 1 antibody|HO antibody|HO-1 antibody|HO1 antibody|Hsp32 antibody

Gen-ID: 3162

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom