HMOX1 Antikörper (N-Term)

Produktnummer ABIN2782158

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HMOX1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Schwein, Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Ziege. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für HMOX1 Antikörper (N-Term) (ABIN2782158)

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HMOX1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: HMOX1 Antibody - N-terminal region

Sequenz: ERPQPDSMPQ DLSEALKEAT KEVHTQAENA EFMRNFQKGQ VTRDGFKLVM

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HMOX1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human HMOX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45222-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HMOX1 Antikörper (ABIN2782158)

Kawahara, Gasperini, Myers, Widrick, Eran, Serafini, Alexander, Pletcher, Morris, Kunkel: "Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling." in: Human molecular genetics, Vol. 23, Issue 7, pp. 1869-78, (2014) (PubMed).

Hausmann, Paul, Kellermeier, Frey, Schölmerich, Falk, Menzel, Fried, Herfarth, Rogler: "(GT)N dinucleotide repeat polymorphism of haem oxygenase-1 promotor region is not associated with inflammatory bowel disease risk or disease course." in: Clinical and experimental immunology, Vol. 153, Issue 1, pp. 81-5, (2008) (PubMed).

Details zu HMOX1

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Andere Bezeichnung: HMOX1

Hintergrund:

Background Information: HMOX1 belongs to the heme oxygenase family. Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2.

Gene Name: Heme oxygenase (decycling) 1

Alternative Symbols: HO-1, HSP32, HMOX1D, bK286B10

Protein Name: Heme oxygenase 1

Molekulargewicht: 33kDa

Gen-ID: 3162

NCBI Accession: NP_002124

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom